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LY 294002 - CAS 154447-36-6

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For Research Use Only | Not For Clinical Use
CATAP154447366-B
CAS154447-36-6
Molecular Weight307.34
DescriptionLY294002, CAS 154447-36-6, is a cell-permeable, potent, reversible, and specific inhibitor of PI 3-kinase ((IC₅₀ = 1.4 µM). Acts on the ATP-binding site.
SolubilityDMSO: 20 mg/mL; ethanol: soluble
Assay≥98% (HPLC)
Coloroff-white
Formsolid; protect from light
Size5MG, 10MG, 25MG
Storage Conditions-20C
1

FAK Blunts Adenosine-Homocysteine-Induced Endothelial Cell Apoptosis: Requirement for PI 3-kinase

Robert E Bellas, Elizabeth O Harrington, Kerri Lynn Sheahan, Julie Newton, Caroline Marcus, Sharon Rounds

Am J Physiol Lung Cell Mol Physiol. 2002 May;282(5):L1135-42.

PMID: 11943680

1

The Activated Insulin-Like Growth Factor I Receptor Induces Depolarization in Breast Epithelial Cells Characterized by Actin Filament Disassembly and Tyrosine Dephosphorylation of FAK, Cas, and Paxillin

M A Guvakova, E Surmacz

Exp Cell Res. 1999 Aug 25;251(1):244-55.

PMID: 10438590

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