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LY255582

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For Research Use Only | Not For Clinical Use
CATAP119193098
CAS119193-09-8
Structure
MDL NumberMFCD00878181
Molecular Weight345.52
InChI KeyLVVHEFJXPXAUDD-BULFRSBZSA-N
Description≥98% (HPLC)
SolubilityDMSO: ≥15 mg/mL
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Activation of Mesolimbic Dopamine Neurons During Novel and Daily Limited Access to Palatable Food Is Blocked by the Opioid Antagonist LY255582

Allison E Sahr, Dana K Sindelar, Jesline T Alexander-Chacko, Brian J Eastwood, Charles H Mitch, Michael A Statnick

Am J Physiol Regul Integr Comp Physiol. 2008 Aug;295(2):R463-71.

PMID: 18525013

1

Localization of Opioid Receptor Antagonist [3H]-LY255582 Binding Sites in Mouse Brain: Comparison With the Distribution of Mu, Delta and Kappa Binding Sites

S L Gackenheimer, T M Suter, J E Pintar, S J Quimby, W J Wheeler, C H Mitch, D R Gehlert, M A Statnick

Neuropeptides. 2005 Dec;39(6):559-67.

PMID: 16289278

1

Peptides That Regulate Food Intake: Antagonism of Opioid Receptors Reduces Body Fat in Obese Rats by Decreasing Food Intake and Stimulating Lipid Utilization

Michael A Statnick, Frank C Tinsley, Brian J Eastwood, Todd M Suter, Charles H Mitch, Mark L Heiman

Am J Physiol Regul Integr Comp Physiol. 2003 Jun;284(6):R1399-408.

PMID: 12736177

1

The Effect of the Opioid Antagonist LY255582 on Body Weight of the Obese Zucker Rat

W N Shaw, C H Mitch, J D Leander, L G Mendelsohn, D M Zimmerman

Int J Obes. 1991 Jun;15(6):387-95.

PMID: 1653188

1

The Protective Role of the Opioid Antagonist LY255582 in the Management of High Fat Diet-Induced Obesity in Adult Male Albino Rats

I Y Ibrahim, H M Ibrahim, N M Aziz, D M Rahman

Endocr Regul. 2015 Oct;49(4):198-205.

PMID: 26494038

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