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LY311727

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For Research Use Only | Not For Clinical Use
CATAP164083845
CAS164083-84-5
Structure
MDL NumberMFCD00943218
Molecular Weight430.43
InChI KeyOPWQYOUZRHDKBR-UHFFFAOYSA-N
Description≥98% (HPLC), powder
SolubilityDMSO: ≥15 mg/mL
Assay≥98% (HPLC)
Colorwhite to tan
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

A Practical, Nenitzescu-Based Synthesis of LY311727, the First Potent and Selective s-PLA(2) Inhibitor

J. M. Pawlak, V. V. Khau, D. R. Hutchison, M. J. Martinelli

J Org Chem. 1996 Dec 13;61(25):9055-9059.

PMID: 11667899

1

Evaluation of Two Inhibitors of Invasion: LY311727 [3-(3-acetamide-1-benzyl-2-ethyl-indolyl-5-oxy)propane Phosphonic Acid] and AEBSF [4-(2-aminoethyl)-benzenesulphonyl Fluoride] in Acute Murine Toxoplasmosis

Rafael Buitrago-Rey, Jorge Olarte, Jorge Enrique Gomez-Marin

J Antimicrob Chemother. 2002 May;49(5):871-4.

PMID: 12003987

1

Mechanical Induction of Group V Phospholipase A(2) Causes Lung Inflammation and Acute Lung Injury

Angelo Y Meliton, Nilda M Muñoz, Lucille N Meliton, Anna A Birukova, Alan R Leff, Konstantin G Birukov

Am J Physiol Lung Cell Mol Physiol. 2013 May 15;304(10):L689-700.

PMID: 23525785

1

Spinal Phospholipase A2 in Inflammatory Hyperalgesia: Role of the Small, Secretory Phospholipase A2

C I Svensson, K K Lucas, X-Y Hua, H C Powell, E A Dennis, T L Yaksh

Neuroscience. 2005;133(2):543-53.

PMID: 15885922

1

VEGF Stimulation of Endothelial Cell PAF Synthesis Is Mediated by Group V 14 kDa Secretory Phospholipase A2

P N Bernatchez, M V Winstead, E A Dennis, M G Sirois

Br J Pharmacol. 2001 Sep;134(1):197-205.

PMID: 11522612

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