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M344

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For Research Use Only | Not For Clinical Use
CATAP251456607-B
CAS251456-60-7
Structure
MDL NumberMFCD03453554
Molecular Weight307.39
InChI KeyMXWDSZWTBOCWBK-UHFFFAOYSA-N
Description≥98% (HPLC), powder
SolubilityDMSO: 10 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size1MG, 5MG
Storage Conditions2-8°C
1

Histone Deacetylase Inhibitor M344 Significantly Improves Nuclear Reprogramming, Blastocyst Quality, and in Vitro Developmental Capacity of Cloned Pig Embryos

L Jin, Q Guo, H-Y Zhu, X-X Xing, G-L Zhang, M-F Xuan, Q-R Luo, Z-B Luo, J-X Wang, H-M Choe, H-J Paek, X-J Yin, J-D Kang

J Anim Sci. 2017 Mar;95(3):1388-1395.

PMID: 28380503

1

M344 Promotes Nonamyloidogenic Amyloid Precursor Protein Processing While Normalizing Alzheimer's Disease Genes and Improving Memory

Claude-Henry Volmar, Hasib Salah-Uddin, Karolina J Janczura, Paul Halley, Guerline Lambert, Andrew Wodrich, Sivan Manoah, Nidhi H Patel, Gregory C Sartor, Neil Mehta, Nancy T H Miles, Sachi Desse, David Dorcius, etc.

Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):E9135-E9144.

PMID: 29073110

1

Pan-HDAC Inhibitors Promote Tau Aggregation by Increasing the Level of Acetylated Tau

Hyeanjeong Jeong, Seulgi Shin, Jun-Seok Lee, Soo Hyun Lee, Ja-Hyun Baik, Sungsu Lim, Yun Kyung Kim

Int J Mol Sci. 2019 Sep 1;20(17):4283.

PMID: 31480543

1

Retraction Notice to "M344 Is a Novel Synthesized Histone Deacetylase Inhibitor That Induces Growth Inhibition, Cell Cycle Arrest, and Apoptosis in Human Endometrial Cancer and Ovarian Cancer Cells" [Gynecol. Oncol. 101 (2006) 108-113]

Gynecol Oncol. 2013 Apr;129(1):270.

PMID: 23638461

1

Selective Histonedeacetylase Inhibitor M344 Intervenes in HIV-1 Latency Through Increasing Histone Acetylation and Activation of NF-kappaB

Hao Ying, Yuhao Zhang, Xin Zhou, Xiying Qu, Pengfei Wang, Sijie Liu, Daru Lu, Huanzhang Zhu

PLoS One. 2012;7(11):e48832.

PMID: 23166597

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