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(−)-Maackiain

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For Research Use Only | Not For Clinical Use
CATAP2035156
CAS2035-15-6
MDL NumberMFCD00270457
Molecular Weight284.26
Assay≥95.0% (HPLC)
Size10MG
Storage Conditions2-8°C
1

Disruption of Heat Shock Protein 90 (Hsp90)-Protein Kinase Cδ (PKCδ) Interaction by (-)-Maackiain Suppresses Histamine H1 Receptor Gene Transcription in HeLa Cells

Yuki Nariai, Hiroyuki Mizuguchi, Takeyasu Ogasawara, Hiroaki Nagai, Yohei Sasaki, Yasunobu Okamoto, Yoshiyuki Yoshimura, Yoshiaki Kitamura, Hisao Nemoto, Noriaki Takeda, Hiroyuki Fukui

J Biol Chem. 2015 Nov 6;290(45):27393-402.

PMID: 26391399

1

Induction of Apoptosis by Maackiain and Trifolirhizin (Maackiain Glycoside) Isolated From Sanzukon (Sophora Subprostrate Chen Et T. Chen) in Human Promyelotic Leukemia HL-60 Cells

Yue Aratanechemuge, Hiroshige Hibasami, Hirotaka Katsuzaki, Kunio Imai, Takashi Komiya

Oncol Rep. 2004 Dec;12(6):1183-8.

PMID: 15547735

1

Maackiain Is a Novel Antiallergic Compound That Suppresses Transcriptional Upregulation of the Histamine H1 Receptor and interleukin-4 Genes

Hiroyuki Mizuguchi, Yuki Nariai, Shuhei Kato, Tomohiro Nakano, Tomoyo Kanayama, Yoshiki Kashiwada, Hisao Nemoto, Kazuyoshi Kawazoe, Yoshihisa Takaishi, Yoshiaki Kitamura, Noriaki Takeda, Hiroyuki Fukui

Pharmacol Res Perspect. 2015 Oct;3(5):e00166.

PMID: 26516579

1

Oxidation of the Phytoalexin Maackiain to 6,6-dihydroxy-maackiain by Colletotrichum Gloeosporioides

S Soby, R Bates, H van Etten

Phytochemistry. 1997 Jul;45(5):925-9.

PMID: 9214775

1

Validated LC-MS/MS Method for the Determination of Maackiain and Its Sulfate and Glucuronide in Blood: Application to Pharmacokinetic and Disposition Studies

Song Gao, Zhen Yang, Taijun Yin, Ming You, Ming Hu

J Pharm Biomed Anal. 2011 May 15;55(2):288-93.

PMID: 21349678

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