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MCC-555

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For Research Use Only | Not For Clinical Use
CATAP161600017
CAS161600-01-7
Structure
Molecular Weight381.42
Description≥98% (HPLC)
SolubilityDMSO: 10 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

A Peroxisome Proliferator-Activated Receptor Ligand MCC-555 Imparts Anti-Proliferative Response in Pancreatic Cancer Cells by PPARgamma-independent Up-Regulation of KLF4

Kyung-Won Min, Xiaobo Zhang, Temjenmongla Imchen, Seung Joon Baek

Toxicol Appl Pharmacol. 2012 Sep 1;263(2):225-32.

PMID: 22750490

1

Characterization of PPAR Dual Ligand MCC-555 in AOM-induced Colorectal Tumorigenesis

Temjenmongla Imchen, Jorden Manasse, Kyung-Won Min, Seung Joon Baek

Exp Toxicol Pathol. 2013 Sep;65(6):919-24.

PMID: 23369238

1

MCC-555-induced NAG-1 Expression Is Mediated in Part by KLF4

Maria Cekanova, Seong-Ho Lee, Michael F McEntee, Seung Joon Baek

Eur J Pharmacol. 2010 Jul 10;637(1-3):30-7.

PMID: 20385121

1

Peroxisome Proliferator-Activated Receptor Ligand MCC-555 Suppresses Intestinal Polyps in ApcMin/+ Mice via Extracellular Signal-Regulated Kinase and Peroxisome Proliferator-Activated Receptor-Dependent Pathways

Kiyoshi Yamaguchi, Maria Cekanova, Michael F McEntee, Joo-Heon Yoon, Susan M Fischer, Ingrid B Renes, Isabelle Van Seuningen, Seung Joon Baek

Mol Cancer Ther. 2008 Sep;7(9):2779-87.

PMID: 18790758

1

Subchronic Toxicity and Toxicokinetics of MCC-555, a Novel Thiazolidinedione, After 270-day Repeated Oral Administration in Dogs

Ning Sun, Guocai Lu, Mei Lin, Guorong Fan, Yutian Wu

Environ Toxicol Pharmacol. 2009 Mar;27(2):237-46.

PMID: 21783946

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