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MDL 105,519

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For Research Use Only | Not For Clinical Use
CATAP161230882
CAS161230-88-2
MDL NumberMFCD00935267
Molecular Weight376.19
InChI KeyLPWVUDLZUVBQGP-FLIBITNWSA-N
Description≥98% (HPLC), solid
SolubilityDMSO: >20 mg/mL
Assay≥98% (HPLC)
Colorwhite to off-white
Formsolid
Size5MG, 25MG
1

[3H]MDL 105,519 Binds With Equal High Affinity to Both Assembled and Unassembled NR1 Subunits of the NMDA Receptor

P L Chazot, C Reiss, B Chopra, F A Stephenson

Eur J Pharmacol. 1998 Jul 17;353(1):137-40.

PMID: 9721050

1

[3H]MDL 105,519, a High-Affinity Radioligand for the N-methyl-D-aspartate Receptor-Associated Glycine Recognition Site

B M Baron, B W Siegel, B L Harrison, R S Gross, C Hawes, P Towers

J Pharmacol Exp Ther. 1996 Oct;279(1):62-8.

PMID: 8858976

1

Characterisation of the Binding of [3H]MDL 105,519, a Radiolabelled Antagonist for the N-methyl-D-aspartate-associated Glycine Site, to Pig Cortical Brain Membranes

G Höfner, K T Wanner

Neurosci Lett. 1997 Apr 25;226(2):79-82.

PMID: 9159494

1

Complex Polyamine Effects on [3H]MDL 105,519 Binding to the NMDA Receptor Glycine Site

T A Sharma, I J Reynolds

Neurochem Int. 1998 Aug;33(2):155-9.

PMID: 9761459

1

Pharmacological Characterization of MDL 105,519, an NMDA Receptor Glycine Site Antagonist

B M Baron, B L Harrison, J H Kehne, C J Schmidt, P L van Giersbergen, H S White, B W Siegel, Y Senyah, T C McCloskey, G M Fadayel, V L Taylor, M K Murawsky, P Nyce, F G Salituro

Eur J Pharmacol. 1997 Apr 4;323(2-3):181-92.

PMID: 9128837

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