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MDL 72527

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For Research Use Only | Not For Clinical Use
CATAP93565016
CAS93565-01-6
MDL NumberMFCD13152261
Molecular Weight265.22
InChI KeyITVRWVVFVHINOH-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityH2O: 15 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to brown
Formpowder
Size5MG, 25MG
Storage Conditionsroom temp
1

Effect of Lysosomotropic Polyamineoxidase Inhibitor MDL-72527 on Platelet Activation

Guoxing Liu, Hang Cao, Guilai Liu, David Heinzmann, Hong Chen, Anja T Umbach, Meinrad Gawaz, Florian Lang

Cell Physiol Biochem. 2016;38(5):1695-702.

PMID: 27160671

1

Effects of MDL 72527, a Specific Inhibitor of Polyamine Oxidase, on Brain Edema, Ischemic Injury Volume, and Tissue Polyamine Levels in Rats After Temporary Middle Cerebral Artery Occlusion

A Doğan, A M Rao, J Hatcher, V L Rao, M K Başkaya, R J Dempsey

J Neurochem. 1999 Feb;72(2):765-70.

PMID: 9930751

1

Interaction of Bovine Serum Amine Oxidase With the Polyamine Oxidase Inactivator MDL 72527

Enzo Agostinelli, Paola Palmigiani, Laura Dalla Vedova, Giampiero Tempera, Francesca Belli, Nikolaus Seiler

Biochem Biophys Res Commun. 2006 Feb 17;340(3):840-4.

PMID: 16380084

1

Targeting Polyamine Oxidase to Prevent Excitotoxicity-Induced Retinal Neurodegeneration

Prahalathan Pichavaram, Chithra Devi Palani, Chintan Patel, Zhimin Xu, Esraa Shosha, Abdelrahman Y Fouda, Ruth B Caldwell, Subhadra Priya Narayanan

Front Neurosci. 2019 Jan 10;12:956.

PMID: 30686964

1

The Polyamine Oxidase Inactivator MDL 72527

Nikolaus Seiler, Benoit Duranton, Francis Raul

Prog Drug Res. 2002;59:1-40.

PMID: 12458962

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