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MDL-860

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For Research Use Only | Not For Clinical Use
CATAP78940622
CAS78940-62-2
MDL NumberMFCD07832293
Molecular Weight309.10
Description≥98% (HPLC)
SolubilityDMSO: 2 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Activity of 2-(3,4-dichlorophenoxy)-5-nitrobenzonitrile (MDL-860) Against Picornaviruses in Vitro

R D Powers, J M Gwaltney Jr, F G Hayden

Antimicrob Agents Chemother. 1982 Oct;22(4):639-42.

PMID: 7181475

1

Allosteric Regulation of Phosphatidylinositol 4-Kinase III Beta by an Antipicornavirus Compound MDL-860

Minetaro Arita, Georgi Dobrikov, Gerhard Pürstinger, Angel S Galabov

ACS Infect Dis. 2017 Aug 11;3(8):585-594.

PMID: 28605587

1

Anti-enteroviral Activity of New MDL-860 Analogues: Synthesis, in vitro/in Vivo Studies and QSAR Analysis

Ivanka Nikolova, Ivaylo Slavchev, Martin Ravutsov, Miroslav Dangalov, Yana Nikolova, Irena Zagranyarska, Adelina Stoyanova, Nadya Nikolova, Lucia Mukova, Petar Grozdanov, Rosica Nikolova, Boris Shivachev, etc.

Bioorg Chem. 2019 Apr;85:487-497.

PMID: 30782563

1

Anti-enteroviral Triple Combination of Viral Replication Inhibitors: Activity Against Coxsackievirus B1 Neuroinfection in Mice

Adelina Stoyanova, Ivanka Nikolova, Gerhard Pürstinger, Georgi Dobrikov, Vladimir Dimitrov, Stefan Philipov, Angel S Galabov

Antivir Chem Chemother. 2015 Dec;24(5-6):136-147.

PMID: 27815331

1

Synthesis and Anti-Enterovirus Activity of New Analogues of MDL-860

Georgi M Dobrikov, Ivaylo Slavchev, Ivanka Nikolova, Adelina Stoyanova, Nadya Nikolova, Lucia Mukova, Rosica Nikolova, Boris Shivachev, Angel S Galabov

Bioorg Med Chem Lett. 2017 Oct 1;27(19):4540-4543.

PMID: 28870395

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