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Merbarone

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For Research Use Only | Not For Clinical Use
CATAP97534219-A
CAS97534-21-9
Structure
MDL NumberMFCD00866337
Molecular Weight263.27
InChI KeyJARCFMKMOFFIGZ-UHFFFAOYSA-N
Description≥98% (HPLC), solid
SolubilityDMSO: >5 mg/mL
Assay≥98% (HPLC)
Formsolid
Size25MG
Storage Conditions2-8°C
1

Dominant Lethal Mutations of Topoisomerase II Inhibitors Etoposide and Merbarone in Male Mice: A Mechanistic Study

Sabry M Attia

Arch Toxicol. 2012 May;86(5):725-31.

PMID: 22207148

1

Expert Opinion on Emerging Urate-Lowering Therapies

Lisa K Stamp, Tony R Merriman, Jasvinder A Singh

Expert Opin Emerg Drugs. 2018 Sep;23(3):201-209.

PMID: 30244605

1

Merbarone Inhibits the Catalytic Activity of Human Topoisomerase IIalpha by Blocking DNA Cleavage

J M Fortune, N Osheroff

J Biol Chem. 1998 Jul 10;273(28):17643-50.

PMID: 9651360

1

Pharmacoinformatics Analysis of Merbarone Binding Site in Human Topoisomerase IIα

Neha Tripathi, Sankar K Guchhait, Prasad V Bharatam

J Mol Graph Model. 2019 Jan;86:1-18.

PMID: 30296751

1

The DNA Topoisomerase II Catalytic Inhibitor Merbarone Is Genotoxic and Induces Endoreduplication

Nuria Pastor, Inmaculada Domínguez, Manuel Luís Orta, Claudia Campanella, Santiago Mateos, Felipe Cortés

Mutat Res. Oct-Nov 2012;738-739:45-51.

PMID: 22921906

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