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Methotrexate

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For Research Use Only | Not For Clinical Use
CATAP59052-B
CAS59-05-2
Structure
MDL NumberMFCD00064370
Molecular Weight454.44
EC Number200-413-8
InChI KeyFBOZXECLQNJBKD-ZDUSSCGKSA-N
REAXYS Number70669
DescriptionPharmaceutical Secondary Standard; Certified Reference Material
Formneat; traceable to USP 1414003
Gradecertified reference material; pharmaceutical secondary standard
Size1G
1

A Review of Methotrexate-Associated Hepatotoxicity

Roopjeet K Bath, Navkiran K Brar, Faripour A Forouhar, George Y Wu

J Dig Dis. 2014 Oct;15(10):517-24.

PMID: 25139707

1

Does Daily Folic Acid Supplementation Reduce Methotrexate Efficacy?

A Cline, J L Jorizzo

Dermatol Online J. 2017 Nov 15;23(11):13030/qt4hf5v2vk.

PMID: 29447631

1

Efficacy and Safety of Tofacitinib Monotherapy, Tofacitinib With Methotrexate, and Adalimumab With Methotrexate in Patients With Rheumatoid Arthritis (ORAL Strategy): A Phase 3b/4, Double-Blind, Head-To-Head, Randomised Controlled Trial

Roy Fleischmann, Eduardo Mysler, Stephen Hall, Alan J Kivitz, Robert J Moots, Zhen Luo, Ryan DeMasi, Koshika Soma, Richard Zhang, Liza Takiya, Svitlana Tatulych, Christopher Mojcik, Sriram Krishnaswami, etc.

Lancet. 2017 Jul 29;390(10093):457-468.

PMID: 28629665

1

Histidine Catabolism Is a Major Determinant of Methotrexate Sensitivity

Naama Kanarek, Heather R Keys, Jason R Cantor, Caroline A Lewis, Sze Ham Chan, Tenzin Kunchok, Monther Abu-Remaileh, Elizaveta Freinkman, Lawrence D Schweitzer, David M Sabatini

Nature. 2018 Jul;559(7715):632-636.

PMID: 29995852

1

Methotrexate Mechanism in Treatment of Rheumatoid Arthritis

Benjamin Friedman, Bruce Cronstein

Joint Bone Spine. 2019 May;86(3):301-307.

PMID: 30081197

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