Methotrexate Related Compound B

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For Research Use Only | Not For Clinical Use

CAT	AP54626-A
CAS	54-62-6
Structure
Molecular Weight	440.41
InChI Key	TVZGACDUOSZQKY-LBPRGKRZSA-N; ε1M/282 nm, 0.1 M NaOH 24,500; ε1M/373 nm, 0.1 M NaOH 8,100
REAXYS Number	69045

Description	United States Pharmacopeia (USP) Reference Standard
Size	75MG

Methotrexate and a Spleen Tyrosine Kinase Inhibitor Cooperate to Inhibit Responses to Peripheral Blood B Cells in Rheumatoid Arthritis

Greg Coffey, Andreas Betz, Jonathan Graf, Gillian Stephens, Pei Hua Lin, John Imboden, Uma Sinha

Pharmacol Res Perspect. 2013 Dec;1(2):e00016.

PMID: 25505569

Non-glutamate Type pyrrolo[2,3-d]pyrimidine Antifolates. III. Synthesis and Biological Properties of N(omega)-masked Ornithine Analogs

F Itoh, Y Yoshioka, K Yukishige, S Yoshida, K Ootsu, H Akimoto

Chem Pharm Bull (Tokyo). 2000 Sep;48(9):1270-80.

PMID: 10993224

Strategies of Reducing the Carcinogenic Risk of Cytostatic Agents on the Basis of Bioassay Evaluation

M R Berger

Neoplasma. 1991;38(4):369-78.

PMID: 1922569

Thymidylate Synthase Level as the Main Predictive Parameter for Sensitivity to 5-fluorouracil, but Not for Folate-Based Thymidylate Synthase Inhibitors, in 13 Nonselected Colon Cancer Cell Lines

B van Triest, H M Pinedo, Y van Hensbergen, K Smid, F Telleman, P S Schoenmakers, C L van der Wilt, J A van Laar, P Noordhuis, G Jansen, G J Peters

Clin Cancer Res. 1999 Mar;5(3):643-54.

PMID: 10100718

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