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MKC-733

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For Research Use Only | Not For Clinical Use
CATAP194093420
CAS194093-42-0
MDL NumberMFCD00939557
Molecular Weight339.84
InChI KeyXGVADZZDFADEOO-YDALLXLXSA-N
Description≥98% (HPLC)
SolubilityH2O: 25 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Drug Evaluation: Pumosetrag for the Treatment of Irritable Bowel Syndrome and Gastroesophageal Reflux Disease

Stefano Evangelista

Curr Opin Investig Drugs. 2007 May;8(5):416-22.

PMID: 17520871

1

Effect of a Novel 5-HT3 Receptor Agonist MKC-733 on Upper Gastrointestinal Motility in Humans

N S Coleman, L Marciani, E Blackshaw, J Wright, M Parker, T Yano, S Yamazaki, P Q Chan, K Wilde, P A Gowland, A C Perkins, R C Spiller

Aliment Pharmacol Ther. 2003 Nov 15;18(10):1039-48.

PMID: 14616171

1

Effect of MKC-733, a 5-HT Receptor Partial Agonist, on Bowel Motility and Symptoms in Subjects With Constipation: An Exploratory Study

T Fujita, S Yokota, M Sawada, M Majima, Y Ohtani, Y Kumagai

J Clin Pharm Ther. 2005 Dec;30(6):611-22.

PMID: 16336295

1

Effects of the Novel 5-HT3 Agonist MKC-733 on the Rat, Mouse and Guinea Pig Digestive Tract

Navinisha Chetty, Helen R Irving, Ian M Coupar

Pharmacology. 2008;81(2):104-9.

PMID: 17952012

1

Inotropic Effects of Prokinetic Agents With 5-HT(4) Receptor Agonist Actions on Human Isolated Myocardial Trabeculae

Wenxia Chai, Kayi Y Chan, René de Vries, Antoon J van den Bogeardt, Joris H de Maeyer, Jan A J Schuurkes, Carlos M Villalón, Pramod R Saxena, A H Jan Danser, Antoinette MaassenVanDenBrink

Life Sci. 2012 Apr 9;90(13-14):538-44.

PMID: 22326501

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