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ML120B

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For Research Use Only | Not For Clinical Use
CATAP783348367
CAS783348-36-7
Molecular Weight366.80
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions−20°C
1

A Selective Small Molecule IkappaB Kinase Beta Inhibitor Blocks Nuclear Factor kappaB-mediated Inflammatory Responses in Human Fibroblast-Like Synoviocytes, Chondrocytes, and Mast Cells

Danyi Wen, Yuhua Nong, Jennifer G Morgan, Pranoti Gangurde, Andrew Bielecki, Jennifer Dasilva, Marie Keaveney, Hong Cheng, Chris Fraser, Lisa Schopf, Michael Hepperle, Geraldine Harriman, Bruce D Jaffee, etc.

J Pharmacol Exp Ther. 2006 Jun;317(3):989-1001.

PMID: 16525037

1

CCL28 Promotes Locomotor Recovery After Spinal Cord Injury via Recruiting Regulatory T Cells

Pengfei Wang, Xiangbei Qi, Guohui Xu, Jianning Liu, Jichao Guo, Xu Li, Xinzhe Ma, Hui Sun

Aging (Albany NY). 2019 Sep 26;11(18):7402-7415.

PMID: 31557129

1

I-kappa-kinase-2 (IKK-2) Inhibition Potentiates Vincristine Cytotoxicity in non-Hodgkin's Lymphoma

Ayad Al-Katib, Alan A Arnold, Amro Aboukameel, Angela Sosin, Peter Smith, Anwar N Mohamed, Frances W Beck, Ramzi M Mohammad

Mol Cancer. 2010 Sep 1;9:228.

PMID: 20809973

1

Natural Modulators of Endosomal Toll-Like Receptor-Mediated Psoriatic Skin Inflammation

Chao-Yang Lai, Yu-Wen Su, Kuo-I Lin, Li-Chung Hsu, Tsung-Hsien Chuang

J Immunol Res. 2017;2017:7807313.

PMID: 28894754

1

Rapid TNFR1-dependent Lymphocyte Depletion in Vivo With a Selective Chemical Inhibitor of IKKbeta

Kumiko Nagashima, Vito G Sasseville, Danyi Wen, Andrew Bielecki, Hua Yang, Chris Simpson, Ethan Grant, Michael Hepperle, Gerry Harriman, Bruce Jaffee, Tim Ocain, Yajun Xu, Christopher C Fraser

Blood. 2006 Jun 1;107(11):4266-73.

PMID: 16439676

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