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ML204

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For Research Use Only | Not For Clinical Use
CATAP5465861
CAS5465-86-1
MDL NumberMFCD00817920
Molecular Weight226.32
InChI KeyUSYRQXDHKXGTCK-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: 5 mg/mL at warmed (clear solution)
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Identification of ML204, a Novel Potent Antagonist That Selectively Modulates Native TRPC4/C5 Ion Channels

Melissa Miller, Jie Shi, Yingmin Zhu, Maksym Kustov, Jin-bin Tian, Amy Stevens, Meng Wu, Jia Xu, Shunyou Long, Pu Yang, Alexander V Zholos, James M Salovich, C David Weaver, Corey R Hopkins, Craig W Lindsley, etc.

J Biol Chem. 2011 Sep 23;286(38):33436-46.

PMID: 21795696

1

Novel Chemical Inhibitor of TRPC4 Channels

Melissa R. Miller, Jie Shi, Meng Wu, Julie Engers, Corey R. Hopkins, Craig W. Lindsley, James M. Salovich, Yingmin Zhu, Jin-Bin Tian, Michael X. Zhu, Owen B. McManus, Min Li

PMID: 22049577

1

Pharmacological Characterization of the Calcium Influx Pathways Involved in Nitric Oxide Production by Endothelial Cells

Janyerson Dannys Pereira da Silva, Gustavo Ballejo

Einstein (Sao Paulo). 2019 Jun 3;17(3):eAO4600.

PMID: 31166411

1

Possible antagonistic effects of the TRPC4 channel blocker ML204 on M 2 and M 3 muscarinic receptors in mouse ileal and detrusor smooth muscles and atrial myocardium

Firoj Alom, Masumi Miyakawa, Hayato Matsuyama, Hiroshi Nagano, Yasuyuki Tanahashi, Toshihiro Unno

J Vet Med Sci. 2018 Sep 13;80(9):1407-1415.

PMID: 29973432

1

Redox TRPs in Diabetes and Diabetic Complications: Mechanisms and Pharmacological Modulation

Pratik Adhya, Shyam Sunder Sharma

Pharmacol Res. 2019 Aug;146:104271.

PMID: 31096011

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