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ML213

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For Research Use Only | Not For Clinical Use
CATAP489402473
CAS489402-47-3
Molecular Weight257.37
Description≥98% (HPLC)
SolubilityDMSO: 5 mg/mL, clear (warmed)
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

A Small Molecule Activator of KCNQ2 and KCNQ4 Channels

Haibo Yu, Meng Wu, Corey Hopkins, Julie Engers, Steve Townsend, Craig Lindsley, Owen B McManus, Min Li

PMID: 23658954

1

Angiotensin II Promotes K V 7.4 Channels Degradation Through Reduced Interaction With HSP90 (Heat Shock Protein 90)

Vincenzo Barrese, Jennifer B Stott, Hericka B Figueiredo, Aisah A Aubdool, Adrian J Hobbs, Thomas A Jepps, Alister J McNeish, Iain A Greenwood

Hypertension. 2018 Jun;71(6):1091-1100.

PMID: 29686000

1

Characterization and Functional Roles of KCNQ-encoded Voltage-Gated Potassium (Kv7) Channels in Human Corpus Cavernosum Smooth Muscle

Jun Ho Lee, Mee Ree Chae, Su Jeong Kang, Hyun Hwan Sung, Deok Hyun Han, Insuk So, Jong Kwan Park, Sung Won Lee

Pflugers Arch. 2020 Jan;472(1):89-102.

PMID: 31919767

1

K V 7 Channel Pharmacological Activation by the Novel Activator ML213: Role for Heteromeric K V 7.4/K V 7.5 Channels in Guinea Pig Detrusor Smooth Muscle Function

Aaron Provence, Damiano Angoli, Georgi V Petkov

J Pharmacol Exp Ther. 2018 Jan;364(1):131-144.

PMID: 29084816

1

Whole-exome Sequencing Identifies Two Novel Mutations in KCNQ4 in Individuals With Nonsyndromic Hearing Loss

Jinsei Jung, Hyun Been Choi, Young Ik Koh, John Hoon Rim, Hye Ji Choi, Sung Huhn Kim, Jae Hyun Lee, Jieun An, Ami Kim, Joon Suk Lee, Sun Young Joo, Seyoung Yu, Jae Young Choi, Tong Mook Kang, Heon Yung Gee

Sci Rep. 2018 Nov 9;8(1):16659.

PMID: 30413759

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