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ML221

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For Research Use Only | Not For Clinical Use
CATAP877636425
CAS877636-42-5
Molecular Weight385.35
Description≥98% (HPLC)
SolubilityDMSO: 5 mg/mL, clear (warmed)
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

An Apelin Receptor Antagonist Prevents Pathological Retinal Angiogenesis With Ischemic Retinopathy in Mice

Yuki Ishimaru, Fumiya Shibagaki, Akiko Yamamuro, Yasuhiro Yoshioka, Sadaaki Maeda

Sci Rep. 2017 Nov 8;7(1):15062.

PMID: 29118394

1

Apelin (APLN) and Apelin Receptor (APLNR) in Human Ovary: Expression, Signaling, and Regulation of Steroidogenesis in Primary Human Luteinized Granulosa Cells

Jennifer Roche, Christelle Ramé, Maxime Reverchon, Namya Mellouk, Marion Cornuau, Fabrice Guerif, Pascal Froment, Joëlle Dupont

Biol Reprod. 2016 Nov;95(5):104.

PMID: 27683264

1

APLN Promotes Hepatocellular Carcinoma Through Activating PI3K/Akt Pathway and Is a Druggable Target

Huarong Chen, Chi-Chun Wong, Dabin Liu, Minnie Y Y Go, Bin Wu, Sui Peng, Ming Kuang, Nathalie Wong, Jun Yu

Theranostics. 2019 Jul 9;9(18):5246-5260.

PMID: 31410213

1

ELABELA, as a Potential Diagnostic Biomarker of Preeclampsia, Regulates Abnormally Shallow Placentation via APJ

Lu Zhou, Hang Sun, Ran Cheng, Xiujun Fan, Shanshan Lai, Cheng Deng

Am J Physiol Endocrinol Metab. 2019 May 1;316(5):E773-E781.

PMID: 30860880

1

Melatonin Prevents Lung Injury by Regulating Apelin 13 to Improve Mitochondrial Dysfunction

Lu Zhang, Fang Li, Xiaomin Su, Yue Li, Yining Wang, Ruonan Fang, Yingying Guo, Tongzhu Jin, Huitong Shan, Xiaoguang Zhao, Rui Yang, Hongli Shan, Haihai Liang

Exp Mol Med. 2019 Jul 4;51(7):73.

PMID: 31273199

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