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ML240

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For Research Use Only | Not For Clinical Use
CATAP1346527987
CAS1346527-98-7
MDL NumberMFCD28137687
Molecular Weight396.44
InChI KeyNHAMBLRUUJAFOY-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: 5 mg/mL, clear (warmed)
Assay≥98% (HPLC)
Color, white to yellow to light brown
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Evaluating p97 Inhibitor Analogues for Potency Against p97-p37 and p97-Npl4-Ufd1 Complexes

Lin Gui, Xiaoyi Zhang, Kelin Li, Kevin J Frankowski, Shan Li, Daniel E Wong, Derek R Moen, Patrick R Porubsky, Henry J Lin, Frank J Schoenen, Tsui-Fen Chou

ChemMedChem. 2016 May 6;11(9):953-7.

PMID: 27043824

1

Evaluating p97 Inhibitor Analogues for Their Domain Selectivity and Potency Against the p97-p47 Complex

Chen-Jie Fang, Lin Gui, Xiaoyi Zhang, Derek R Moen, Kelin Li, Kevin J Frankowski, Henry J Lin, Frank J Schoenen, Tsui-Fen Chou

ChemMedChem. 2015 Jan;10(1):52-6.

PMID: 25377500

1

Selective, Reversible Inhibitors of the AAA ATPase p97

Tsui-Fen Chou, Kelin Li, Brian E. Nordin, Patrick Porubsky, Kevin Frankowski, Mathew P. Patricelli, Jeffrey Aubé, Frank J. Schoenen, Raymond Deshaies

PMID: 23658965

1

Structure-activity Relationship Study Reveals ML240 and ML241 as Potent and Selective Inhibitors of p97 ATPase

Tsui-Fen Chou, Kelin Li, Kevin J Frankowski, Frank J Schoenen, Raymond J Deshaies

ChemMedChem. 2013 Feb;8(2):297-312.

PMID: 23316025

1

VCP Inhibitors Induce Endoplasmic Reticulum Stress, Cause Cell Cycle Arrest, Trigger Caspase-Mediated Cell Death and Synergistically Kill Ovarian Cancer Cells in Combination With Salubrinal

Prabhakar Bastola, Lisa Neums, Frank J Schoenen, Jeremy Chien

Mol Oncol. 2016 Dec;10(10):1559-1574.

PMID: 27729194

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