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ML289

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For Research Use Only | Not For Clinical Use
CATAP1382481799
CAS1382481-79-9
Molecular Weight349.42
Description≥98% (HPLC)
SolubilityDMSO: 10 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Development of a Novel, CNS-penetrant, Metabotropic Glutamate Receptor 3 (mGlu3) NAM Probe (ML289) Derived From a Closely Related mGlu5 PAM

Douglas J Sheffler, Cody J Wenthur, Joshua A Bruner, Sheridan J S Carrington, Paige N Vinson, Kiran K Gogi, Anna L Blobaum, Ryan D Morrison, Mitchell Vamos, Nicholas D P Cosford, Shaun R Stauffer, J Scott Daniels, etc.

Bioorg Med Chem Lett. 2012 Jun 15;22(12):3921-5.

PMID: 22607673

1

Development of a Second Generation mGlu

Cody Wenthur, J. Scott Daniels, Ryan Morrison, Julie L. Engers, Colleen M. Niswender, P. Jeffrey Conn, Craig W. Lindsley

PMID: 23885366

1

Development of the First Selective mGlu 3 NAM from an mGlu 5 PAM Hit

Douglas J. Sheffler, Cody J. Wenthur, Joshua A. Brunner, J. Scott Daniels, Ryan D. Morrison, Anna L. Blobaum, Eric S. Dawson, Julie L. Engers, Colleen M. Niswender, P. Jeffrey Conn, Craig W. Lindsley

PMID: 23762947

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