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ML298

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For Research Use Only | Not For Clinical Use
CATAP1426916020
CAS1426916-02-0
Molecular Weight432.44
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

A Next Generation PLD2 Inhibitor With Improved Physiochemical Properties and DMPK Profile for Translational in Vivo

Matthew C. O'Reilly, Sarah A. Scott, J. Scott Daniels, Ryan Morrison, Julie L. Engers, Thomas Oguin, Paul Thomas, H. Alex Brown, Craig W. Lindsley

PMID: 25834904

1

Development of a Selective, Allosteric PLD2 Inhibitor

Sarah A. Scott, Matthew C. O'Reilly, J. Scott Daniels, Ryan Morrison, Roger Ptak, Eric S. Dawson, Nichole Tower, Julie L. Engers, Darren W. Engers, Thomas Oguin, Paul Thomas, Lucille White, H. Alex Brown, etc.

PMID: 23762931

1

Development of Dual PLD1/2 and PLD2 Selective Inhibitors From a Common 1,3,8-Triazaspiro[4.5]decane Core: Discovery of Ml298 and Ml299 That Decrease Invasive Migration in U87-MG Glioblastoma Cells

Matthew C O'Reilly, Sarah A Scott, Kyle A Brown, Thomas H Oguin 3rd, Paul G Thomas, J Scott Daniels, Ryan Morrison, H Alex Brown, Craig W Lindsley

J Med Chem. 2013 Mar 28;56(6):2695-9.

PMID: 23445448

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