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ML323

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For Research Use Only | Not For Clinical Use
CATAP1572414835
CAS1572414-83-5
Molecular Weight384.48
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

A Selective USP1-UAF1 Inhibitor Links Deubiquitination to DNA Damage Responses

Qin Liang, Thomas S Dexheimer, Ping Zhang, Andrew S Rosenthal, Mark A Villamil, Changjun You, Qiuting Zhang, Junjun Chen, Christine A Ott, Hongmao Sun, Diane K Luci, Bifeng Yuan, Anton Simeonov, Ajit Jadhav, etc.

Nat Chem Biol. 2014 Apr;10(4):298-304.

PMID: 24531842

1

Inhibition of Ubiquitin Specific Protease 1 Sensitizes Colorectal Cancer Cells to DNA-Damaging Chemotherapeutics

Xin Xu, Shaoyan Li, Ximao Cui, Kunkun Han, Jun Wang, Xiaodan Hou, Long Cui, Songbing He, Jiecheng Xiao, Yili Yang

Front Oncol. 2019 Dec 18;9:1406.

PMID: 31921663

1

The Role of the Complex USP1/WDR48 in Differentiation and Proliferation Processes in Cancer Stem Cells

Jussara Maria Goncalves, Mabel Mariela Rodriguez Cordeiro, Elena Riet Correa Rivero

Curr Stem Cell Res Ther. 2017;12(5):416-422.

PMID: 28302046

1

USP1 Inhibition Destabilizes KPNA2 and Suppresses Breast Cancer Metastasis

Aihui Ma, Ming Tang, Li Zhang, Boshi Wang, Zhaojuan Yang, Yun Liu, Guiqin Xu, Lin Wu, Tiantian Jing, Xiaoli Xu, Shengli Yang, Yongzhong Liu

Oncogene. 2019 Mar;38(13):2405-2419.

PMID: 30531833

1

USP1-UAF1 Deubiquitinase Complex Stabilizes TBK1 and Enhances Antiviral Responses

Zhongxia Yu, Hui Song, Mutian Jia, Jintao Zhang, Wenwen Wang, Qi Li, Lining Zhang, Wei Zhao

J Exp Med. 2017 Dec 4;214(12):3553-3563.

PMID: 29138248

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