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ML324

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For Research Use Only | Not For Clinical Use
CATAP1222800794
CAS1222800-79-4
MDL NumberMFCD28053518
Molecular Weight349.43
InChI KeyQDBVSOZTVKXUES-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: 10 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to light brown
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Discovery of ML324, a JMJD2 Demethylase Inhibitor With Demonstrated Antiviral Activity

Ganesha Rai, Akane Kawamura, Anthony Tumber, Yu Liang, Jodi L. Vogel, Jesse H. Arbuckle, Nathan R. Rose, Thomas S. Dexheimer, Timothy L. Foley, Oliver N. King, Amy Quinn, Bryan T. Mott, Christopher J. Schofield, etc.

PMID: 24260783

1

Histone Lysine Demethylases of JMJD2 or KDM4 Family Are Important Epigenetic Regulators in Reward Circuitry in the Etiopathology of Depression

Salil Saurav Pathak, Swati Maitra, Sumana Chakravarty, Arvind Kumar

Neuropsychopharmacology. 2017 Mar;42(4):854-863.

PMID: 27711046

1

Inhibition of KDM4A Activity as a Strategy to Suppress interleukin-6 Production and Attenuate Colitis Induction

Kazuhiro Ishiguro, Osamu Watanabe, Masanao Nakamura, Takeshi Yamamura, Masanobu Matsushita, Hidemi Goto, Yoshiki Hirooka

Clin Immunol. 2017 Jul;180:120-127.

PMID: 28511912

1

Inhibition of the Histone Demethylase KDM4B Leads to Activation of KDM1A, Attenuates Bacterial-Induced Pro-Inflammatory Cytokine Release, and Reduces Osteoclastogenesis

Joy E Kirkpatrick, Keith L Kirkwood, Patrick M Woster

Epigenetics. 2018;13(5):557-572.

PMID: 29927684

1

KDM4B Histone Demethylase and G9a Regulate Expression of Vascular Adhesion Proteins in Cerebral Microvessels

Ji-Young Choi, Sang-Sun Yoon, Sang-Eun Kim, Sangmee Ahn Jo

Sci Rep. 2017 Mar 22;7:45005.

PMID: 28327608

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