CAS 89159-60-4 ML354 - Analytical Products / Alfa Chemistry

CAT	AP89159604
CAS	89159-60-4
Structure
MDL Number	MFCD00593702
Molecular Weight	282.29
InChI Key	GNJUKVGDCUKDLF-UHFFFAOYSA-N

Description	≥98% (HPLC)
Solubility	H2O: 10 mg/mL, clear; DMSO: 25 mg/mL, clear
Assay	≥98% (HPLC)
Color	white to beige
Form	powder
Size	5MG, 25MG
Storage Conditions	−20°C

1

A Novel and Selective PAR4 Antagonist: ML354

Summer E. Young, Matthew T. Duvernay, Michael L. Schulte, Kellie D. Nance, Bruce J. Melancon, Julie Engers, Michael R. Wood, Heidi E. Hamm, Craig W. Lindsley

PMID: 25834897

1

Molecular Requirements Involving the Human Platelet Protease-Activated receptor-4 Mechanism of Activation by Peptide Analogues of Its Tethered-Ligand

I C Moschonas, T F Kellici, T Mavromoustakos, P Stathopoulos, V Tsikaris, V Magafa, A G Tzakos, A D Tselepis

Platelets. 2017 Dec;28(8):812-821.

PMID: 28267389

1

Platelet Depletion Limits the Severity but Does Not Prevent the Occurrence of Experimental Transfusion-Related Acute Lung Injury

Fabrice Cognasse, Sofiane Tariket, Hind Hamzeh-Cognasse, Charles-Antoine Arthaud, Marie-Ange Eyraud, Thomas Bourlet, Philippe Berthelot, Sandrine Laradi, Sebastien Fauteux-Daniel, Olivier Garraud

Transfusion. 2020 Apr;60(4):713-723.

PMID: 32108957

1

Substituted Indoles as Selective Protease Activated Receptor 4 (PAR-4) Antagonists: Discovery and SAR of ML354

Wandong Wen, Summer E Young, Matthew T Duvernay, Michael L Schulte, Kellie D Nance, Bruce J Melancon, Julie Engers, Charles W Locuson 2nd, Michael R Wood, J Scott Daniels, Wenjun Wu, Craig W Lindsley, Heidi E Hamm, etc.

Bioorg Med Chem Lett. 2014 Oct 1;24(19):4708-4713.

PMID: 25176330

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