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MLL1/WDR5/Ash2L/RbBP5/DPY30 human

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For Research Use Only | Not For Clinical Use
CATIAR42416110
Descriptionrecombinant, expressed in E. coli, ≥83% (SDS-PAGE)
Assay≥83% (SDS-PAGE)
Formaqueous solution; 27 kDa (MLL1); 35 kDa (WDR5); 60 kDa (RbBP5); 61 kDa (Ash2L); NM_005057 (RbBP5); NM_005933 (MLL1); NM_017588 (WDR5); NM_032574 (DPY30)
Size50μG
Storage Conditions−70°C
1

A Non-Active-Site SET Domain Surface Crucial for the Interaction of MLL1 and the RbBP5/Ash2L Heterodimer Within MLL Family Core Complexes

Stephen A Shinsky, Michael Hu, Valarie E Vought, Sarah B Ng, Michael J Bamshad, Jay Shendure, Michael S Cosgrove

J Mol Biol. 2014 Jun 12;426(12):2283-99.

PMID: 24680668

1

Targeted Disruption of the Interaction Between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes

Nilda L Alicea-Velázquez, Stephen A Shinsky, Daniel M Loh, Jeong-Heon Lee, David G Skalnik, Michael S Cosgrove

J Biol Chem. 2016 Oct 21;291(43):22357-22372.

PMID: 27563068

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