MLL1/WDR5/Ash2L/RbBP5 human - Analytical Products / Alfa Chemistry

CAT

IAR42416111

Description	recombinant, expressed in E. coli, ≥83% (SDS-PAGE)
Assay	≥83% (SDS-PAGE)
Form	aqueous solution; 35 kDa (WDR5); 60 kDa (RbBP5); 61 kDa (Ash2L); NM_005057 (RbBP5); NM_005933 (MLL1); NM_017588 (WDR5); NM_032574 (DPY30)
Size	50μG
Storage Conditions	−70°C

1

Structural Basis for Activity Regulation of MLL Family Methyltransferases

Yanjing Li, Jianming Han, Yuebin Zhang, Fang Cao, Zhijun Liu, Shuai Li, Jian Wu, Chunyi Hu, Yan Wang, Jin Shuai, Juan Chen, Liaoran Cao, Dangsheng Li, Pan Shi, Changlin Tian, Jian Zhang, Yali Dou, Guohui Li, etc.

Nature. 2016 Feb 25;530(7591):447-52.

PMID: 26886794

1

Structural Basis of Nucleosome Recognition and Modification by MLL Methyltransferases

Han Xue, Tonghui Yao, Mi Cao, Guanjun Zhu, Yan Li, Guiyong Yuan, Yong Chen, Ming Lei, Jing Huang

Nature. 2019 Sep;573(7774):445-449.

PMID: 31485071

1

Targeting Human SET1/MLL Family of Proteins

Masoud Vedadi, Levi Blazer, Mohammad S Eram, Dalia Barsyte-Lovejoy, Cheryl H Arrowsmith, Taraneh Hajian

Protein Sci. 2017 Apr;26(4):662-676.

PMID: 28160335

1

The Development of Inhibitors Targeting the Mixed Lineage Leukemia 1 (MLL1)-WD Repeat Domain 5 Protein (WDR5) Protein-Protein Interaction

Xiaoqing Ye, Gang Chen, Jia Jin, Binzhong Zhang, Yinda Wang, Fei Ye

Curr Med Chem. 2019 May 27.

PMID: 31132972

1

The Internal Interaction in RBBP5 Regulates Assembly and Activity of MLL1 Methyltransferase Complex

Jianming Han, Tingting Li, Yanjing Li, Muchun Li, Xiaoman Wang, Chao Peng, Chen Su, Na Li, Yiwen Li, Ying Xu, Yong Chen

Nucleic Acids Res. 2019 Nov 4;47(19):10426-10438.

PMID: 31544921

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