MMP-2/MMP-9 Substrate II - Analytical Products / Alfa Chemistry

CAT	IAR42416007
Molecular Weight	655.85

Description	An exceptional thiopeptide that is used as a substrate for the rapid, sensitive, and continuous spectrophotometric assay of Type IV collagenases, MMP-2 (gelatinase A), and MMP-9 (gelatinase B).
Solubility	water: 1 mg/mL; 50% acetic acid: 10 mg/mL
Assay	≥97% (HPLC)
Color	white
Form	solid; protect from light
Size	5MG
Storage Conditions	-20C

1

A Unique Substrate Recognition Profile for Matrix metalloproteinase-2

Emily I Chen, Steven J Kridel, Eric W Howard, Weizhong Li, Adam Godzik, Jeffrey W Smith

J Biol Chem. 2002 Feb 8;277(6):4485-91.

PMID: 11694539

1

Contributions of the MMP-2 Collagen Binding Domain to Gelatin Cleavage. Substrate Binding via the Collagen Binding Domain Is Required for Hydrolysis of Gelatin but Not Short Peptides

Xiaoping Xu, Yao Wang, Janelle L Lauer-Fields, Gregg B Fields, Bjorn Steffensen

Matrix Biol. 2004 Jun;23(3):171-81.

PMID: 15296945

1

Functional Basis for the Overlap in Ligand Interactions and Substrate Specificities of Matrix metalloproteinases-9 and -2

Xiaoping Xu, Zhihua Chen, Yao Wang, Yoshishige Yamada, Bjorn Steffensen

Biochem J. 2005 Nov 15;392(Pt 1):127-34.

PMID: 16008524

1

Identification of Amino Acid Residues of the Matrix metalloproteinase-2 Essential for Its Selective Inhibition by Beta-Amyloid Precursor Protein-Derived Inhibitor

Shouichi Higashi, Kaoru Miyazaki

J Biol Chem. 2008 Apr 11;283(15):10068-78.

PMID: 18238779

1

Selective Modulation of Matrix Metalloproteinase 9 (MMP-9) Functions via Exosite Inhibition

Janelle L Lauer-Fields, John K Whitehead, Shunzi Li, Robert P Hammer, Keith Brew, Gregg B Fields

J Biol Chem. 2008 Jul 18;283(29):20087-95.

PMID: 18499673

* Products or Services Interested: MMP-2/MMP-9 Substrate II ()
* Your question
* Name
* Email
Verification Code