MMP-2 Substrate, Fluorogenic

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For Research Use Only | Not For Clinical Use

CAT	IAR42416003
Molecular Weight	1093.15

Description	A quenched fluorescence substrate for MMP-2 (gelatinase A; kcat/Km = 3.97 x 10⁵ M⁻¹s⁻¹).
Solubility	DMSO: 10 mg/mL; λem ~393 nm
Assay	≥95% (HPLC)
Color	yellow
Form	lyophilized solid; desiccated; protect from light
Size	1MG
Storage Conditions	-20C

Bone Sialoprotein Does Not Interact With Pro-Gelatinase A (MMP-2) or Mediate MMP-2 Activation

Queena Hwang, Sela Cheifetz, Christopher M Overall, Christopher A McCulloch, Jaro Sodek

BMC Cancer. 2009 Apr 22;9:121.

PMID: 19386107

Design and Characterization of a Fluorogenic Substrate Selectively Hydrolyzed by Stromelysin 1 (Matrix metalloproteinase-3)

H Nagase, C G Fields, G B Fields

J Biol Chem. 1994 Aug 19;269(33):20952-7.

PMID: 8063713

Detection of MMP-2 and MMP-9 Activity in Vivo With a Triple-Helical Peptide Optical Probe

Walter J Akers, Baogang Xu, Hyeran Lee, Gail P Sudlow, Gregg B Fields, Samuel Achilefu, W Barry Edwards

Bioconjug Chem. 2012 Mar 21;23(3):656-63.

PMID: 22309692

Phosphorylation Status of 72 kDa MMP-2 Determines Its Structure and Activity in Response to Peroxynitrite

Anna Laura Jacob-Ferreira, Marcia Yuri Kondo, Pravas Kumar Baral, Michael N G James, Andrew Holt, Xiaohu Fan, Richard Schulz

PLoS One. 2013 Aug 27;8(8):e71794.

PMID: 24013357

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