MMP-7 Substrate, Fluorogenic

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For Research Use Only | Not For Clinical Use

CAT	IAR42416008
Molecular Weight	1164.27

Description	Excellent fluorogenic substrate for MMP-7 (kcat/Km = 1.9 x 10⁵ M⁻¹ s⁻¹).
Solubility	10% acetic acid: 1 mg/mL; λem ~360 nm
Assay	≥90% (HPLC)
Color	yellow
Form	solid; desiccated; protect from light
Size	1MG
Storage Conditions	-20C

Development of a Novel Fluorogenic Proteolytic Beacon for in Vivo Detection and Imaging of Tumour-Associated Matrix metalloproteinase-7 Activity

J Oliver McIntyre, Barbara Fingleton, K Sam Wells, David W Piston, Conor C Lynch, Shiva Gautam, Lynn M Matrisian

Biochem J. 2004 Feb 1;377(Pt 3):617-28.

PMID: 14556651

Evaluation of Fluorometric and Zymographic Methods as Activity Assays for Stromelysins and Gelatinases

A R Quesada, M M Barbacid, E Mira, P Fernández-Resa, G Márquez, M Aracil

Clin Exp Metastasis. 1997 Jan;15(1):26-32.

PMID: 9009103

New Insights Into the Substrate Specificity of Macrophage Elastase MMP-12

Anne-Sophie Lamort, Rodolphe Gravier, Anni Laffitte, Luiz Juliano, Marie-Louise Zani, Thierry Moreau

Biol Chem. 2016 May;397(5):469-84.

PMID: 26760307

Role of the S1' Subsite Glutamine 215 in Activity and Specificity of stromelysin-3 by Site-Directed Mutagenesis

B Holtz, P Cuniasse, A Boulay, R Kannan, A Mucha, F Beau, P Basset, V Dive

Biochemistry. 1999 Sep 14;38(37):12174-9.

PMID: 10508422

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