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Monastrol

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For Research Use Only | Not For Clinical Use
CATAP254753543
CAS254753-54-3
Structure
MDL NumberMFCD00813077
Molecular Weight292.35
InChI KeyLOBCDGHHHHGHFA-UHFFFAOYSA-N
Description≥98% (HPLC), solid
SolubilityDMSO: >5 mg/mL
Assay≥98% (HPLC)
Colorwhite to off-white
Formsolid
MP185-185.9 °C (lit.)
Size1MG, 5MG
Storage Conditions2-8°C
1

Circular RNA‑MTO1 Suppresses Breast Cancer Cell Viability and Reverses Monastrol Resistance Through Regulating the TRAF4/Eg5 Axis

Yunxiao Liu, Yanyan Dong, Liping Zhao, Lihong Su, Jin Luo

Int J Oncol. 2018 Oct;53(4):1752-1762.

PMID: 30015883

1

Comparison of the Effects of Monastrol and Oxomonastrol on Human Hepatoma Cell Line HepG2/C3A

Lilian Areal Marques, Simone Cristine Semprebon, Daniele Sartori, Ângelo DE Fátima, Lúcia Regina Ribeiro, Mário Sérgio Mantovani

Anticancer Res. 2017 Mar;37(3):1197-1204.

PMID: 28314282

1

Fatty-monastrol Derivatives and Its Cytotoxic Effect Against Melanoma Cell Growth

Milene Medeiros de Moraes, Tamara Germani Marinho Treptow, Wystan Kreisly Othon Teixeira, Luciana Almeida Piovesan, Marcelo Gonçalves Montes D'Oca, Ana Paula de Souza Votto

Bioorg Chem. 2017 Jun;72:148-155.

PMID: 28460356

1

Mitotic Slippage and Expression of Survivin Are Linked to Differential Sensitivity of Human Cancer Cell-Lines to the Kinesin-5 Inhibitor Monastrol

Hila Asraf, Rachel Avunie-Masala, Michal Hershfinkel, Larisa Gheber

PLoS One. 2015 Jun 2;10(6):e0129255.

PMID: 26035434

1

Monastrol, a 3,4-dihydropyrimidin-2(1H)-thione, as structural scaffold for the development of modulators for GHB high-affinity binding sites and α 1 β 2 δ GABA A receptors

Maria Damgaard, Anas Al-Khawaja, Mia Nittegaard-Nielsen, Rebekka F Petersen, Petrine Wellendorph, Bente Frølund

Eur J Med Chem. 2017 Sep 29;138:300-312.

PMID: 28683403

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