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β-Muricholic Acid

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For Research Use Only | Not For Clinical Use
CATAP2393591
CAS2393-59-1
Structure
MDL NumberMFCD00271403
Molecular Weight408.57
Description≥98% (HPLC)
SolubilityDMSO: 2 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions−20°C
1

FXR Regulates Intestinal Cancer Stem Cell Proliferation

Ting Fu, Sally Coulter, Eiji Yoshihara, Tae Gyu Oh, Sungsoon Fang, Fritz Cayabyab, Qiyun Zhu, Tong Zhang, Mathias Leblanc, Sihao Liu, Mingxiao He, Wanda Waizenegger, Emanuel Gasser, Bernd Schnabl, Annette R Atkins, etc.

Cell. 2019 Feb 21;176(5):1098-1112.e18.

PMID: 30794774

1

Gut Microbiota Regulates Bile Acid Metabolism by Reducing the Levels of Tauro-Beta-Muricholic Acid, a Naturally Occurring FXR Antagonist

Sama I Sayin, Annika Wahlström, Jenny Felin, Sirkku Jäntti, Hanns-Ulrich Marschall, Krister Bamberg, Bo Angelin, Tuulia Hyötyläinen, Matej Orešič, Fredrik Bäckhed

Cell Metab. 2013 Feb 5;17(2):225-35.

PMID: 23395169

1

Identification of Urine tauro-β-muricholic Acid as a Promising Biomarker in Polygoni Multiflori Radix-induced Hepatotoxicity by Targeted Metabolomics of Bile Acids

Dong-Sheng Zhao, Li-Long Jiang, Ya-Xi Fan, Lei-Chi Dong, Jiang Ma, Xin Dong, Xiao-Jun Xu, Ping Li, Hui-Jun Li

Food Chem Toxicol. 2017 Oct;108(Pt B):532-542.

PMID: 28237774

1

Tauro-β-muricholic Acid Restricts Bile Acid-Induced Hepatocellular Apoptosis by Preserving the Mitochondrial Membrane Potential

Gerald Ulrich Denk, Carl Philipp Kleiss, Ralf Wimmer, Timo Vennegeerts, Florian Paul Reiter, Sabine Schulz, Hans Zischka, Christian Rust

Biochem Biophys Res Commun. 2012 Aug 10;424(4):758-64.

PMID: 22809502

1

The Metabolism of Chenodeoxycholic Acid to Beta-Muricholic Acid in Rat Liver

K M Botham, G S Boyd

Eur J Biochem. 1983 Jul 15;134(1):191-6.

PMID: 6861760

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