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N-(2-Chloroethyl)-N-ethyl-2-bromobenzylamine hydrochloride

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For Research Use Only | Not For Clinical Use
CATAP40616759
CAS40616-75-9
Structure
MDL NumberMFCD00043241
Molecular Weight313.06
InChI KeyNDDRNRRNYOULND-UHFFFAOYSA-N
REAXYS Number4020910
Description≥98%, solid
SolubilityH2O: 48 mg/mL; 0.1 M NaOH: 7 mg/mL; ethanol: soluble
Assay≥98%
Colorwhite
Formsolid
Size100MG, 250MG
1

Investigation of Behavioral Dysfunctions Induced by Monoamine Depletions in a Mouse Model of Parkinson's Disease

Yong Li, Qian Jiao, Xixun Du, Mingxia Bi, Shuaishuai Han, Lingling Jiao, Hong Jiang

Front Cell Neurosci. 2018 Aug 8;12:241.

PMID: 30135645

1

Neurotoxicity of N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine Hydrochloride (DSP 4) on Noradrenergic Neurons Is Mimicked by Its Cyclic Aziridinium Derivative

L M Zieher, G Jaim-Etcheverry

Eur J Pharmacol. 1980 Jul 25;65(2-3):249-56.

PMID: 7398788

1

Noradrenergic Neurotoxin, N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine Hydrochloride (DSP-4), Treatment Eliminates Estrogenic Effects on Song Responsiveness in Female Zebra Finches (Taeniopygia Guttata)

Akshat Vyas, Cheryl Harding, Joseph McGowan, Randall Snare, Diane Bogdan

Behav Neurosci. 2008 Oct;122(5):1148-57.

PMID: 18823170

1

The Aziridinium Derivative of DSP4 (N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine) Accelerates the Beating Rate of Isolated Rat Atria by Enhancing the Spontaneous Release of Noradrenaline

M E Landa, M C Rubio, G Jaim-Etcheverry

Naunyn Schmiedebergs Arch Pharmacol. 1987 Oct;336(4):396-402.

PMID: 3431596

1

The Neurotoxic Compound N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine Hydrochloride (DSP4) Depletes Endogenous Norepinephrine and Enhances Release of [3H]norepinephrine From Rat Cortical Slices

M E Landa, M C Rubio, G Jaim-Etcheverry

J Pharmacol Exp Ther. 1984 Oct;231(1):131-6.

PMID: 6491970

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