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N-Octanoyl-D-sphingosine

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For Research Use Only | Not For Clinical Use
CATIAR4244376
MDL NumberMFCD00236496
Molecular Weight425.69
InChI KeyAPDLCSPGWPLYEQ-WRBRXSDHSA-N
Descriptionwaxy solid
SolubilityDMSO or ethanol: soluble
Formwaxy solid
Size5MG
Storage Conditions−20°C
1

Ceramide Is a Competitive Inhibitor of Diacylglycerol Kinase in Vitro and in Intact Human Leukemia (HL-60) Cells

A Younes, D W Kahn, J M Besterman, R Bittman, H S Byun, R N Kolesnick

J Biol Chem. 1992 Jan 15;267(2):842-7.

PMID: 1309777

1

Novel Ceramide Analogs as Potential Chemotherapeutic Agents in Breast Cancer

Amanda P Struckhoff, Robert Bittman, Matthew E Burow, Sanda Clejan, Steven Elliott, Timothy Hammond, Yan Tang, Barbara S Beckman

J Pharmacol Exp Ther. 2004 May;309(2):523-32.

PMID: 14742741

1

Novel D: -Erythro N-octanoyl Sphingosine Analogs as Chemo- And Endocrine-Resistant Breast Cancer Therapeutics

James W Antoon, Jiawang Liu, Adharsh P Ponnapakkam, Matthew M Gestaut, Maryam Foroozesh, Barbara S Beckman

Cancer Chemother Pharmacol. 2010 May;65(6):1191-5.

PMID: 20155475

1

Short Chain Ceramides as Substrates for Glucocerebroside Synthetase. Differences Between Liver and Brain Enzymes

R R Vunnam, N S Radin

Biochim Biophys Acta. 1979 Apr 27;573(1):73-82.

PMID: 454641

1

Stereospecific Induction of Apoptosis in U937 Cells by N-octanoyl-sphingosine Stereoisomers and N-octyl-sphingosine. The Ceramide Amide Group Is Not Required for Apoptosis

N Karasavvas, R K Erukulla, R Bittman, R Lockshin, Z Zakeri

Eur J Biochem. 1996 Mar 1;236(2):729-37.

PMID: 8612651

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