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Naringin

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For Research Use Only | Not For Clinical Use
CATAP10236472-A
CAS10236-47-2
Structure
MDL NumberMFCD00148888
SynonymsNaringoside, Naringin (6CI,7CI,8CI), Naringenin 7-O-neohesperidoside, Aurantiin, Naringenin 7-β-neohesperidoside, (2S)-Naringin, 4H-1-Benzopyran-4-one, 7-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-, (S)-, 7-[2-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyloxy]-2,3-dihydro-4',5,7-trihydroxyflavone, NSC 5548,4H-1-Benzopyran-4-one, 7-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-, (2S)-, Naringenin 7-neohesperidoside
IUPAC Name(2S)-7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one
Molecular Weight580.53
Molecular FormulaC27H32O14
EC Number233-566-4
Canonical SMILESC[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2Oc3cc(O)c4C(=O)C[C@H](Oc4c3)c5ccc(O)cc5)[C@H](O)[C@H](O)[C@H]1O
InChIInChI=1S/C27H32O14/c1-10-20(32)22(34)24(36)26(37-10)41-25-23(35)21(33)18(9-28)40-27(25)38-13-6-14(30)19-15(31)8-16(39-17(19)7-13)11-2-4-12(29)5-3-11/h2-7,10,16,18,20-30,32-36H,8-9H2,1H3/t10-,16-,18+,20-,21+,22+,23-,24+,25+,26-,27+/m0/s1
InChI KeyDFPMSGMNTNDNHN-JJLSSNRUSA-N
REAXYS Number102012
Descriptionanalytical standard
Accurate Mass580.1792
Assay≥95.0% (HPLC)
Formneat; gas chromatography (GC): suitable
FormatNeat
Gradeanalytical standard; analytical standard
Size25MG, 500MG
1

Naringin Enhances Endothelial Progenitor Cell (EPC) Proliferation and Tube Formation Capacity Through the CXCL12/CXCR4/PI3K/Akt Signaling Pathway

Zhihu Zhao, Xinlong Ma, Jianxiong Ma, Xiaolei Sun, Fengbo Li, Jianwei Lv

Chem Biol Interact. 2018 Apr 25;286:45-51.

PMID: 29510123

1

Naringin Inhibits Lipopolysaccharide-Induced Activation of Microglia Cells

Jie Bai, Siyuan Li, Gang Wu, Lei Ma, Chen Li, Hongtao Liu, Pengbo Zhang

Cell Mol Biol (Noisy-le-grand). 2019 Jun 30;65(5):38-42.

PMID: 31304904

1

Preclinical Evidence for the Pharmacological Actions of Naringin: A Review

Saurabh Bharti, Neha Rani, Bhaskar Krishnamurthy, Dharamvir Singh Arya

Planta Med. 2014 Apr;80(6):437-51.

PMID: 24710903

1

Protective Effect of Naringin on DSS-Induced Ulcerative Colitis in Mice

Hongyang Cao, Jiuxi Liu, Peng Shen, Jiapei Cai, Yuchang Han, Kunpeng Zhu, Yunhe Fu, Naisheng Zhang, Zecai Zhang, Yongguo Cao

J Agric Food Chem. 2018 Dec 19;66(50):13133-13140.

PMID: 30472831

1

Therapeutic Potential of Naringin: An Overview

Rui Chen, Qiao-Ling Qi, Meng-Ting Wang, Qi-Yan Li

Pharm Biol. 2016 Dec;54(12):3203-3210.

PMID: 27564838

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