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Necrostatin-7

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For Research Use Only | Not For Clinical Use
CATAP351062083
CAS351062-08-3
MDL NumberMFCD02334728
Molecular Weight371.41
InChI KeySMJGLNVGTJLIRV-UHFFFAOYSA-N
Description≥98% (HPLC), powder
SolubilityDMSO: >10 mg/mL (with warming)
Assay≥98% (HPLC)
Coloryellow to tan
Formpowder
Size5MG
Storage Conditions2-8°C
1

[CARDIOPROTFETIVE EFECTS OF NECROSTATIN-7 IN THE RAT MODEL OF PERMANENT CORONARY OCCLUSION]

Yu V Dmitriev, A A Karpov, A V Dracheva, S M Minasian, S G Chefu, L V Vasina, E A Demchenko, I M M Galagudza

Ross Fiziol Zh Im I M Sechenova. 2015 Apr;101(4):408-14.

PMID: 26336739

1

Necrostatin-7 Suppresses RANK-NFATc1 Signaling and Attenuates Macrophage to Osteoclast Differentiation

Hiroaki Fuji, Saori Ohmae, Naruto Noma, Masatoshi Takeiri, Hideto Yasutomi, Kazuya Izumi, Moe Ito, Masayasu Toyomoto, Soichiro Iwaki, Kenji Takemoto, Satoru Seo, Kojiro Taura, Shigeaki Hida, Mineyoshi Aoyama, etc.

Biochem Biophys Res Commun. 2018 Sep 5;503(2):544-549.

PMID: 29800570

1

Sestrin2 Is Induced by Glucose Starvation via the Unfolded Protein Response and Protects Cells From Non-Canonical Necroptotic Cell Death

Boxiao Ding, Anita Parmigiani, Ajit S Divakaruni, Kellie Archer, Anne N Murphy, Andrei V Budanov

Sci Rep. 2016 Mar 2;6:22538.

PMID: 26932729

1

Structure-activity Relationship Study of a Novel Necroptosis Inhibitor, necrostatin-7

Weihong Zheng, Alexei Degterev, Emily Hsu, Junying Yuan, Chengye Yuan

Bioorg Med Chem Lett. 2008 Sep 15;18(18):4932-5.

PMID: 18768316

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