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Neferine

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For Research Use Only | Not For Clinical Use
CATAP2292162
CAS2292-16-2
Structure
MDL NumberMFCD22416529
Molecular Weight624.77
InChI KeyMIBATSHDJRIUJK-ZWXJPIIXSA-N
Description≥98% (HPLC)
SolubilityDMSO: >15 mg/mL
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder; protect from light
Size5MG, 25MG
Storage Conditions2-8°C
1

FAK and S6K1 Inhibitor, Neferine, Dually Induces Autophagy and Apoptosis in Human Neuroblastoma Cells

Dinh-Chuong Pham, Yu-Chuan Chang, Shian-Ren Lin, Yuh-Ming Fuh, May-Jywan Tsai, Ching-Feng Weng

Molecules. 2018 Nov 28;23(12):3110.

PMID: 30486505

1

Neferine Inhibits LPS-ATP-induced Endothelial Cell Pyroptosis via Regulation of ROS/NLRP3/Caspase-1 Signaling Pathway

Yang-Shuo Tang, Yan-Hua Zhao, Yong Zhong, Xiao-Zhao Li, Jia-Xi Pu, Yan-Cheng Luo, Qiao-Ling Zhou

Inflamm Res. 2019 Sep;68(9):727-738.

PMID: 31172209

1

Neferine Promotes GLUT4 Expression and Fusion With the Plasma Membrane to Induce Glucose Uptake in L6 Cells

Ping Zhao, Di Tian, Guanjun Song, Qian Ming, Jia Liu, Jinhua Shen, Qing-Hua Liu, Xinzhou Yang

Front Pharmacol. 2019 Sep 4;10:999.

PMID: 31551792

1

Neferine-induced Apoptosis Is Dependent on the Suppression of Bcl-2 Expression via Downregulation of p65 in Renal Cancer Cells

Eun-Ae Kim, Eon-Gi Sung, In-Hwan Song, Joo-Young Kim, Hwa-Jung Sung, Ho-Yong Sohn, Jong-Yi Park, Tae-Jin Lee

Acta Biochim Biophys Sin (Shanghai). 2019 Jul 10;51(7):734-742.

PMID: 31187116

1

Pharmacological Actions of Neferine in the Modulation of Human Platelet Function

Ru-Ping Yang, Ya-Jun Zhou, Wei Song, Zhao Yin, Ao-Di He, Zhang-Yin Ming

Eur J Pharmacol. 2019 Nov 5;862:172626.

PMID: 31445013

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