Nek7, Active human - Analytical Products / Alfa Chemistry

CAT	IAR42411904
MDL Number	MFCD07785452

Description	recombinant, expressed in E. coli, ≥85% (SDS-PAGE), buffered aqueous glycerol solution
Assay	≥85% (SDS-PAGE)
Form	buffered aqueous glycerol solution
Size	5μG
Storage Conditions	−70°C

1

An Autoinhibitory Tyrosine Motif in the Cell-Cycle-Regulated Nek7 Kinase Is Released Through Binding of Nek9

Mark W Richards, Laura O'Regan, Corine Mas-Droux, Joelle M Y Blot, Jack Cheung, Swen Hoelder, Andrew M Fry, Richard Bayliss

Mol Cell. 2009 Nov 25;36(4):560-70.

PMID: 19941817

1

Mammalian Target of Rapamycin (mTOR) and the Proteasome Attenuates IL-1β Expression in Primary Mouse Cardiac Fibroblasts

May-Kristin Torp, Kuan Yang, Trine Ranheim, Knut Husø Lauritzen, Katrine Alfsnes, Leif E Vinge, Pål Aukrust, Kåre-Olav Stensløkken, Arne Yndestad, Øystein Sandanger

Front Immunol. 2019 Jun 6;10:1285.

PMID: 31244838

1

Molecular Mechanisms of Human IRE1 Activation Through Dimerization and Ligand Binding

Amar Joshi, Yvette Newbatt, P Craig McAndrew, Mark Stubbs, Rosemary Burke, Mark W Richards, Chitra Bhatia, John J Caldwell, Tatiana McHardy, Ian Collins, Richard Bayliss

Oncotarget. 2015 May 30;6(15):13019-35.

PMID: 25968568

1

Oridonin Is a Covalent NLRP3 Inhibitor With Strong Anti-Inflammasome Activity

Hongbin He, Hua Jiang, Yun Chen, Jin Ye, Aoli Wang, Chao Wang, Qingsong Liu, Gaolin Liang, Xianming Deng, Wei Jiang, Rongbin Zhou

Nat Commun. 2018 Jun 29;9(1):2550.

PMID: 29959312

1

Structural Mechanism for NEK7-licensed Activation of NLRP3 Inflammasome

Humayun Sharif, Li Wang, Wei Li Wang, Venkat Giri Magupalli, Liudmila Andreeva, Qi Qiao, Arthur V Hauenstein, Zhaolong Wu, Gabriel Núñez, Youdong Mao, Hao Wu

Nature. 2019 Jun;570(7761):338-343.

PMID: 31189953

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