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NH125

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For Research Use Only | Not For Clinical Use
CATAP278603080-B
CAS278603-08-0
MDL NumberMFCD07370143
Molecular Weight524.56
InChI KeyRVWOHCBHAGBLLT-UHFFFAOYSA-M
Description≥98% (HPLC), solid
SolubilityDMSO: >20 mg/mL
Assay≥98% (HPLC)
Colorwhite to off-white
Formsolid
MP88.2-94.9 °C
Size5MG, 25MG
Storage Conditions−20°C
1

An Integrated Stress Response Agent That Modulates DR5-Dependent TRAIL Synergy Reduces Patient-Derived Glioma Stem Cell Viability

Saad Sheikh, Deeksha Saxena, Xiaobing Tian, Ahmad Amirshaghaghi, Andrew Tsourkas, Steven Brem, Jay F Dorsey

Mol Cancer Res. 2019 May;17(5):1102-1114.

PMID: 30642878

1

Antimicrobial Peptide-Inspired NH125 Analogues: Bacterial and Fungal Biofilm-Eradicating Agents and Rapid Killers of MRSA Persisters

Akash Basak, Yasmeen Abouelhassan, Ran Zuo, Hussain Yousaf, Yousong Ding, Robert W Huigens

Org Biomol Chem. 2017 Jul 5;15(26):5503-5512.

PMID: 28534905

1

Influence of Subinhibitory Concentrations of NH125 on Biofilm Formation & Virulence Factors of Staphylococcus Aureus

Qingzhong Liu, Zhaojun Zheng, Wooseong Kim, Beth Burgwyn Fuchs, Eleftherios Mylonakis

Future Med Chem. 2018 Jun 1;10(11):1319-1331.

PMID: 29846088

1

NH125 Kills Methicillin-Resistant Staphylococcus Aureus Persisters by Lipid Bilayer Disruption

Wooseong Kim, Nico Fricke, Annie L Conery, Beth Burgwyn Fuchs, Rajmohan Rajamuthiah, Elamparithi Jayamani, Petia M Vlahovska, Frederick M Ausubel, Eleftherios Mylonakis

Future Med Chem. 2016;8(3):257-69.

PMID: 26910612

1

NH125 Reduces the Level of CPEB3, an RNA Binding Protein, to Promote Synaptic GluA2 Expression

Crhistian L Bender, Qian Yang, Lu Sun, Siqiong June Liu

Neuropharmacology. 2016 Feb;101:531-7.

PMID: 25842244

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