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NIBR-0213

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For Research Use Only | Not For Clinical Use
CATAP1233332143
CAS1233332-14-3
MDL NumberMFCD25977008
Molecular Weight464.98
Description≥98% (HPLC)
SolubilityDMSO: 2 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions−20°C
1

A Potent and Selective S1P(1) Antagonist With Efficacy in Experimental Autoimmune Encephalomyelitis

Jean Quancard, Birgit Bollbuck, Philipp Janser, Daniela Angst, Frédéric Berst, Peter Buehlmayer, Markus Streiff, Christian Beerli, Volker Brinkmann, Danilo Guerini, Paul A Smith, Timothy J Seabrook, Martin Traebert, etc.

Chem Biol. 2012 Sep 21;19(9):1142-51.

PMID: 22999882

1

Fine-tuning S1P Therapeutics

Hideru Obinata, Timothy Hla

Chem Biol. 2012 Sep 21;19(9):1080-2.

PMID: 22999874

1

Pathophysiological Consequences of a Break in S1P1-Dependent Homeostasis of Vascular Permeability Revealed by S1P1 Competitive Antagonism

Marc Bigaud, Zuhal Dincer, Birgit Bollbuck, Janet Dawson, Nicolau Beckmann, Christian Beerli, Gina Fishli-Cavelti, Michaela Nahler, Daniela Angst, Philipp Janser, Heike Otto, Elisabeth Rosner, Rene Hersperger, etc.

PLoS One. 2016 Dec 22;11(12):e0168252.

PMID: 28005953

1

Siponimod (BAF312) Activates Nrf2 While Hampering NFκB in Human Astrocytes, and Protects From Astrocyte-Induced Neurodegeneration

Emanuela Colombo, Claudia Bassani, Anthea De Angelis, Francesca Ruffini, Linda Ottoboni, Giancarlo Comi, Gianvito Martino, Cinthia Farina

Front Immunol. 2020 Apr 8;11:635.

PMID: 32322257

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