NMDA Receptor NR2BCT(1292-1304)-TAT - Analytical Products / Alfa Chemistry

CAT	IAR4249502
Molecular Weight	3381.96

Description	A 13-mer NMDA receptor 2B (NR2B) subunit carboxy terminal (1292-1304) derived peptide that specifically binds DAPK1 in a reversible manner and antagonizes the activated DAPK1-NR2B interaction and the potentiation of NMDAR function
Solubility	water: 50 mg/mL
Assay	≥98% (HPLC)
Color	white
Form	powder; desiccated; protect from light
Size	2MG
Storage Conditions	-20C

1

Dynamic Plasticity of NMDA Receptor-Mediated Calcium Entry in Neurons Exposed to HIV-tat

Gabriela K Popescu

J Neurochem. 2014 Sep;130(5):609-11.

PMID: 24785658

1

HIV-Tat Induces the Nrf2/ARE Pathway Through NMDA Receptor-Elicited Spermine Oxidase Activation in Human Neuroblastoma Cells

Roberta Mastrantonio, Manuela Cervelli, Stefano Pietropaoli, Paolo Mariottini, Marco Colasanti, Tiziana Persichini

PLoS One. 2016 Feb 19;11(2):e0149802.

PMID: 26895301

1

NMDA Receptor Activation by HIV-Tat Protein Is Clade Dependent

Wenxue Li, Yan Huang, Rollie Reid, Joseph Steiner, Tanya Malpica-Llanos, Thomas A Darden, Susarla K Shankar, Anita Mahadevan, Parthasarthy Satishchandra, Avindra Nath

J Neurosci. 2008 Nov 19;28(47):12190-8.

PMID: 19020013

1

Oligodendrocytes Are Targets of HIV-1 Tat: NMDA and AMPA Receptor-Mediated Effects on Survival and Development

Shiping Zou, Babette Fuss, Sylvia Fitting, Yun Kyung Hahn, Kurt F Hauser, Pamela E Knapp

J Neurosci. 2015 Aug 12;35(32):11384-98.

PMID: 26269645

1

Subtype Selective NMDA Receptor Antagonists Induce Recovery of Synapses Lost Following Exposure to HIV-1 Tat

A H Shin, H J Kim, S A Thayer

Br J Pharmacol. 2012 Jun;166(3):1002-17.

PMID: 22142193

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