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NMNAT1 human

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For Research Use Only | Not For Clinical Use
CATIAR42415160
Descriptionrecombinant, expressed in E. coli, His tagged, >95% (SDS-PAGE)
Assay>95% (SDS-PAGE)
Colorclear
Formliquid
Size10μG
Storage Conditions−20°C
1

A ribose-functionalized NAD + with unexpected high activity and selectivity for protein poly-ADP-ribosylation

Xiao-Nan Zhang, Qinqin Cheng, Jingwen Chen, Albert T Lam, Yanran Lu, Zhefu Dai, Hua Pei, Nikolai M Evdokimov, Stan G Louie, Yong Zhang

Nat Commun. 2019 Sep 13;10(1):4196.

PMID: 31519936

1

Genome-wide Linkage and Sequence Analysis Challenge CCDC66 as a Human Retinal Dystrophy Candidate Gene and Support a Distinct NMNAT1-related Fundus Phenotype

A O Khan, B S Budde, P Nürnberg, A Kawalia, S Lenzner, H J Bolz

Clin Genet. 2018 Jan;93(1):149-154.

PMID: 28369829

1

Mouse Models of NMNAT1-Leber Congenital Amaurosis (LCA9) Recapitulate Key Features of the Human Disease

Scott H Greenwald, Jeremy R Charette, Magdalena Staniszewska, Lan Ying Shi, Steve D M Brown, Lisa Stone, Qin Liu, Wanda L Hicks, Gayle B Collin, Michael R Bowl, Mark P Krebs, Patsy M Nishina, Eric A Pierce

Am J Pathol. 2016 Jul;186(7):1925-1938.

PMID: 27207593

1

NAD + augmentation restores mitophagy and limits accelerated aging in Werner syndrome

Evandro F Fang, Yujun Hou, Sofie Lautrup, Martin Borch Jensen, Beimeng Yang, Tanima SenGupta, Domenica Caponio, Rojyar Khezri, Tyler G Demarest, Yahyah Aman, David Figueroa, Marya Morevati, Ho-Joon Lee, etc.

Nat Commun. 2019 Nov 21;10(1):5284.

PMID: 31754102

1

NAD-biosynthetic Enzyme NMNAT1 Reduces Early Behavioral Impairment in the Htau Mouse Model of Tauopathy

Francesca Rossi, Philippine C Geiszler, Weina Meng, Matthew R Barron, Malcolm Prior, Anna Herd-Smith, Andrea Loreto, Maria Yanez Lopez, Henryk Faas, Marie-Christine Pardon, Laura Conforti

Behav Brain Res. 2018 Feb 26;339:140-152.

PMID: 29175372

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