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NQTrp

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For Research Use Only | Not For Clinical Use
CATAP185351193
CAS185351-19-3
MDL NumberMFCD21496345
Molecular Weight360.36
InChI KeyDZZUYZXINNHEGM-SFHVURJKSA-N
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Color, orange to dark orange-red
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Cl-NQTrp Alleviates Tauopathy Symptoms in a Model Organism Through the Inhibition of Tau Aggregation-Engendered Toxicity

Moran Frenkel-Pinter, Sharon Tal, Roni Scherzer-Attali, Malak Abu-Hussien, Idan Alyagor, Tal Eisenbaum, Ehud Gazit, Daniel Segal

Neurodegener Dis. 2017;17(2-3):73-82.

PMID: 27760426

1

Inhibitory Effect of Naphthoquinone-Tryptophan Hybrid Towards Aggregation of PAP f39 Semen Amyloid

Guru KrishnaKumar Viswanathan, Satabdee Mohapatra, Ashim Paul, Elad Arad, Raz Jelinek, Ehud Gazit, Daniel Segal

Molecules. 2018 Dec 11;23(12):3279.

PMID: 30544943

1

Mechanistic Insights Into Remodeled Tau-derived PHF6 Peptide Fibrils by Naphthoquinone-Tryptophan Hybrids

V Guru KrishnaKumar, Ashim Paul, Ehud Gazit, Daniel Segal

Sci Rep. 2018 Jan 8;8(1):71.

PMID: 29311706

1

Naphthoquinone Tryptophan Hybrids: A Promising Small Molecule Scaffold for Mitigating Aggregation of Amyloidogenic Proteins and Peptides

Guru KrishnaKumar Viswanathan, Ashim Paul, Ehud Gazit, Daniel Segal

Front Cell Dev Biol. 2019 Oct 17;7:242.

PMID: 31750300

1

Novel Mannitol-Based Small Molecules for Inhibiting Aggregation of α-Synuclein Amyloids in Parkinson's Disease

Ashim Paul, Bo-Dou Zhang, Satabdee Mohapatra, Gao Li, Yan-Mei Li, Ehud Gazit, Daniel Segal

Front Mol Biosci. 2019 Mar 22;6:16.

PMID: 30968030

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