NS-398 - CAS 123653-11-2

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For Research Use Only | Not For Clinical Use
Molecular Weight314.36
DescriptionA cell-permeable selective inhibitor of COX-2 in vitro.
SolubilityDMSO: 20 mg/mL
Assay≥98% (TLC)
Colorpale yellow
Storage Conditions+15C to +30C

1Effect of Nimesulide Action Time Dependence on Selectivity Towards Prostaglandin G/H synthase/cyclooxygenase Activity

T Vago, M Bevilacqua, G Norbiato

Arzneimittelforschung. 1995 Oct;45(10):1096-8.

PMID: 8595067

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1The cyclooxygenase-2 Inhibitor NS-398 Inhibits Proliferation and Induces Apoptosis in Human Osteosarcoma Cells via Downregulation of the Survivin Pathway

Da-Peng Duan, Xiao-Qian Dang, Kun-Zheng Wang, Yong-Ping Wang, Hui Zhang, Wu-Lin You

Oncol Rep. 2012 Nov;28(5):1693-700.

PMID: 22922684

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