NSC 617145

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For Research Use Only | Not For Clinical Use
Molecular Weight400.04
Description≥98% (HPLC)
SolubilityDMSO: 3 mg/mL, clear (warmed)
Assay≥98% (HPLC)
Colorwhite to light brown
Size5MG, 25MG
Storage Conditions2-8°C

1Targeting an Achilles' Heel of Cancer With a WRN Helicase Inhibitor

Monika Aggarwal, Taraswi Banerjee, Joshua A Sommers, Robert M Brosh Jr

Cell Cycle. 2013 Oct 15;12(20):3329-35.

PMID: 24036544

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1Werner Syndrome Helicase Has a Critical Role in DNA Damage Responses in the Absence of a Functional Fanconi Anemia Pathway

Monika Aggarwal, Taraswi Banerjee, Joshua A Sommers, Chiara Iannascoli, Pietro Pichierri, Robert H Shoemaker, Robert M Brosh Jr

Cancer Res. 2013 Sep 1;73(17):5497-507.

PMID: 23867477

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1WRN-targeted Therapy Using Inhibitors NSC 19630 and NSC 617145 Induce Apoptosis in HTLV-1-transformed Adult T-cell Leukemia Cells

R Moles, X T Bai, H Chaib-Mezrag, C Nicot

J Hematol Oncol. 2016 Nov 9;9(1):121.

PMID: 27829440

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