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NSC23766 trihydrochloride

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For Research Use Only | Not For Clinical Use
CATAP1177865176
CAS1177865-17-6
Molecular Weight530.96
Description≥97% (HPLC)
SolubilityH2O: 10 mg/mL, clear
Assay≥97% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions−20°C
1

Activation of Macrophages by a Laccase-Polymerized Polyphenol Is Dependent on Phosphorylation of Rac1

Katsuya Tajima, Satoshi Akanuma, Akiko Matsumoto-Akanuma, Daisuke Yamanaka, Ken-Ichi Ishibashi, Yoshiyuki Adachi, Naohito Ohno

Biochem Biophys Res Commun. 2018 Jan 15;495(3):2209-2213.

PMID: 29269293

1

Maladaptive Dendritic Spine Remodeling Contributes to Diabetic Neuropathic Pain

Andrew M Tan, Omar A Samad, Tanya Z Fischer, Peng Zhao, Anna-Karin Persson, Stephen G Waxman

J Neurosci. 2012 May 16;32(20):6795-807.

PMID: 22593049

1

NSC23766, a Widely Used Inhibitor of Rac1 Activation, Additionally Acts as a Competitive Antagonist at Muscarinic Acetylcholine Receptors

Magdolna Levay, Kurt Allen Krobert, Karola Wittig, Niels Voigt, Marcel Bermudez, Gerhard Wolber, Dobromir Dobrev, Finn Olav Levy, Thomas Wieland

J Pharmacol Exp Ther. 2013 Oct;347(1):69-79.

PMID: 23887096

1

Rac1 Regulates Platelet Shedding of CD40L in Abdominal Sepsis

Rundk Hwaiz, Milladur Rahman, Enming Zhang, Henrik Thorlacius

Lab Invest. 2014 Sep;94(9):1054-63.

PMID: 25046439

1

TIAM1-RAC1 Signalling Axis-Mediated Activation of NADPH oxidase-2 Initiates Mitochondrial Damage in the Development of Diabetic Retinopathy

Renu A Kowluru, Anjaneyulu Kowluru, Rajakrishnan Veluthakal, Ghulam Mohammad, Ismail Syed, Julia M Santos, Manish Mishra

Diabetologia. 2014 May;57(5):1047-56.

PMID: 24554007

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