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Nutlin-3

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For Research Use Only | Not For Clinical Use
CATAP548472680
CAS548472-68-0
Structure
MDL NumberMFCD11977784
Molecular Weight581.49
InChI KeyBDUHCSBCVGXTJM-IZLXSDGUSA-N
Description≥98% (HPLC), powder
SolubilityDMSO: 20 mg/mL; H2O: insoluble
Assay≥98% (HPLC)
Formpowder
Size1MG, 5MG
Storage Conditions−20°C
1

Nutlin-3 Enhances the Bortezomib Sensitivity of p53-defective Cancer Cells by Inducing Paraptosis

Dong Min Lee, In Young Kim, Min Ji Seo, Mi Ri Kwon, Kyeong Sook Choi

Exp Mol Med. 2017 Aug 11;49(8):e365.

PMID: 28798402

1

Nutlin-3 Sensitizes Nasopharyngeal Carcinoma Cells to Cisplatin-Induced Cytotoxicity

Yee-Lin Voon, Munirah Ahmad, Pooi-Fong Wong, Roslina Husaini, Wayne Tiong-Weng Ng, Chee-Onn Leong, David Philip Lane, Alan Soo-Beng Khoo

Oncol Rep. 2015 Oct;34(4):1692-700.

PMID: 26252575

1

Nutlin-3, A p53-Mdm2 Antagonist for Nasopharyngeal Carcinoma Treatment

Voon Yee-Lin, Wong Pooi-Fong, Alan Khoo Soo-Beng

Mini Rev Med Chem. 2018;18(2):173-183.

PMID: 28714398

1

Nutlin-3, an Antagonist of MDM2, Enhances the Radiosensitivity of Esophageal Squamous Cancer With Wild-Type p53

Tianli He, Jiayou Guo, Hongmei Song, Hongcheng Zhu, Xiaoke Di, Hua Min, Yuandong Wang, Guangzong Chen, Wangshu Dai, Jianhua Ma, Xinchen Sun, Jianxin Ma

Pathol Oncol Res. 2018 Jan;24(1):75-81.

PMID: 28341911

1

Nutlin-3-Induced Sensitization of Non-Small Cell Lung Cancer Stem Cells to Axitinib-Induced Apoptosis Through Repression of Akt1/Wnt Signaling

Meng Wang, Xin Wang, Yuan Li, Qiang Xiao, Xiao-Hai Cui, Guo-Dong Xiao, Ji-Chang Wang, Chong-Wen Xu, Hong Ren, Dapeng Liu

Oncol Res. 2019 Sep 23;27(9):987-995.

PMID: 30832755

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