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Olinone

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For Research Use Only | Not For Clinical Use
CATIAR4244413
Molecular Weight299.37
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions−20°C
1

Electro-mechanical Effects of 3, 4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)-qu Inolinone (OPC-8212), a New Positive Inotropic Agent. Isolated Adult Canine Purkinje Strands and Ventricular Trabeculae

D A Lathrop, A Schwartz

Arzneimittelforschung. 1984;34(3A):371-5.

PMID: 6540090

1

In Silico Design and Molecular Basis for the Selectivity of Olinone Toward the First Over the Second Bromodomain of BRD4

Yoel Rodríguez, Guillermo Gerona-Navarro, Roman Osman, Ming-Ming Zhou

Proteins. 2020 Mar;88(3):414-430.

PMID: 31587361

1

Nonequivalent Response to Bromodomain-Targeting BET Inhibitors in Oligodendrocyte Cell Fate Decision

Cheng-Ming Chiang

Chem Biol. 2014 Jul 17;21(7):804-6.

PMID: 25036774

1

Photoreceptor Protection via Blockade of BET Epigenetic Readers in a Murine Model of Inherited Retinal Degeneration

Lei Zhao, Jun Li, Yingmei Fu, Mengxue Zhang, Bowen Wang, Jonathan Ouellette, Pawan K Shahi, Bikash R Pattnaik, Jyoti J Watters, Wai T Wong, Lian-Wang Guo

J Neuroinflammation. 2017 Jan 19;14(1):14.

PMID: 28103888

1

Synthesis and Elaboration of N-methylpyrrolidone as an Acetamide Fragment Substitute in Bromodomain Inhibition

J P Hilton-Proctor, O Ilyichova, Z Zheng, I G Jennings, R W Johnstone, J Shortt, S J Mountford, M J Scanlon, P E Thompson

Bioorg Med Chem. 2019 Dec 15;27(24):115157.

PMID: 31727451

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