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Oltipraz

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For Research Use Only | Not For Clinical Use
CATAP64224211
CAS64224-21-1
MDL NumberMFCD00868499
Molecular Weight226.34
EC Number264-736-6
InChI KeyCKNAQFVBEHDJQV-UHFFFAOYSA-N
Description≥98% (HPLC), powder
SolubilityDMSO: >20 mg/mL
Assay≥98% (HPLC)
Colorred
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Analgesic and Antidepressant Effects of Oltipraz on Neuropathic Pain in Mice by Modulating Microglial Activation

Andrés Felipe Díaz, Sara Polo, Núria Gallardo, Sergi Leánez, Olga Pol

J Clin Med. 2019 Jun 21;8(6):890.

PMID: 31234342

1

Deleterious Effect of Oltipraz on Extrahepatic Cholestasis in Bile Duct-Ligated Mice

Jittima Weerachayaphorn, Yuhuan Luo, Albert Mennone, Carol J Soroka, Kathy Harry, James L Boyer

J Hepatol. 2014 Jan;60(1):160-6.

PMID: 23978715

1

Nrf2 Deficiency Upregulates Intrarenal Angiotensin-Converting Enzyme-2 and Angiotensin 1-7 Receptor Expression and Attenuates Hypertension and Nephropathy in Diabetic Mice

Shuiling Zhao, Anindya Ghosh, Chao-Sheng Lo, Isabelle Chenier, James W Scholey, Janos G Filep, Julie R Ingelfinger, Shao-Ling Zhang, John S D Chan

Endocrinology. 2018 Feb 1;159(2):836-852.

PMID: 29211853

1

Pharmacokinetic Interaction Between Oltipraz and Omeprazole in Rats: Competitive Inhibition of Metabolism of Oltipraz by Omeprazole via CYP1A1 and 3A2, and of Omeprazole by Oltipraz via CYP1A1/2, 2D1/2, and 3A1/2

Dae Y Lee, Jin W Kim, Myung G Lee

Eur J Pharm Sci. 2007 Dec;32(4-5):328-39.

PMID: 17935951

1

Size and Temporal-Dependent Efficacy of Oltipraz-Loaded PLGA Nanoparticles for Treatment of Acute Kidney Injury and Fibrosis

Hang Yu, Tingsheng Lin, Wei Chen, Wenmin Cao, Chengwei Zhang, Tianwei Wang, Meng Ding, Sheng Zhao, Hui Wei, Hongqian Guo, Xiaozhi Zhao

Biomaterials. 2019 Oct;219:119368.

PMID: 31349200

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