CAS 868273-06-7 Org 27569 - Analytical Products / Alfa Chemistry

CAT	AP868273067
CAS	868273-06-7
Structure
MDL Number	MFCD11045300
Molecular Weight	409.95
EC Number	278-169-7
InChI Key	AHFZDNYNXFMRFQ-UHFFFAOYSA-N

Description	≥98% (HPLC)
Solubility	H2O: <2 mg/mL; DMSO: >5 mg/mL
Assay	≥98% (HPLC)
Color	white
Form	powder
Size	10MG
Storage Conditions	2-8°C

1

A Key Agonist-Induced Conformational Change in the Cannabinoid Receptor CB1 Is Blocked by the Allosteric Ligand Org 27569

Jonathan F Fay, David L Farrens

J Biol Chem. 2012 Sep 28;287(40):33873-82.

PMID: 22846992

1

CB(1) Receptor Allosteric Modulators Display Both Agonist and Signaling Pathway Specificity

Gemma L Baillie, James G Horswill, Sharon Anavi-Goffer, Patricia H Reggio, Daniele Bolognini, Mary E Abood, Sean McAllister, Phillip G Strange, Gary J Stephens, Roger G Pertwee, Ruth A Ross

Mol Pharmacol. 2013 Feb;83(2):322-38.

PMID: 23160940

1

Effects of the Cannabinoid CB₁ Receptor Allosteric Modulator ORG 27569 on Reinstatement of Cocaine- And Methamphetamine-Seeking Behavior in Rats

Li Jing, Yanyan Qiu, Yanan Zhang, Jun-Xu Li

Drug Alcohol Depend. 2014 Oct 1;143:251-6.

PMID: 25169627

1

In-vivo Pharmacological Evaluation of the CB1-receptor Allosteric Modulator Org-27569

Thomas F Gamage, Bogna M Ignatowska-Jankowska, Jenny L Wiley, Mostafa Abdelrahman, Laurent Trembleau, Iain R Greig, Ganesh A Thakur, Ritesh Tichkule, Justin Poklis, Ruth A Ross, Roger G Pertwee, Aron H Lichtman

Behav Pharmacol. 2014 Apr;25(2):182-5.

PMID: 24603340

1

Structural Dynamics and Energetics Underlying Allosteric Inactivation of the Cannabinoid Receptor CB1

Jonathan F Fay, David L Farrens

Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):8469-74.

PMID: 26100912

* Products or Services Interested: Org 27569 (868273-06-7)
* Your question
* Name
* Email
Verification Code