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ORM-10103

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For Research Use Only | Not For Clinical Use
CATAP488847285
CAS488847-28-5
Structure
Molecular Weight348.35
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to light brown
Formpowder
Size5MG, 25MG
Storage Conditionsroom temp
1

Comparison of the Efficiency of Na+/Ca2+ Exchanger or Na+/H+ Exchanger Inhibition and Their Combination in Reducing Coronary Reperfusion-Induced Arrhythmias

J Szepesi, K Acsai, Z Sebok, J Prorok, P Pollesello, J Levijoki, J Gy Papp, A Varro, A Toth

J Physiol Pharmacol. 2015 Apr;66(2):215-26.

PMID: 25903952

1

Efficacy of Selective NCX Inhibition by ORM-10103 During Simulated ischemia/reperfusion

Anita Kormos, Norbert Nagy, Károly Acsai, Krisztina Váczi, Szabina Ágoston, Piero Pollesello, Jouko Levijoki, Norbert Szentandrássy, Julius Gy Papp, András Varró, András Tóth

Eur J Pharmacol. 2014 Oct 5;740:539-51.

PMID: 24975099

1

ORM-10103, a Novel Specific Inhibitor of the Na+/Ca2+ Exchanger, Decreases Early and Delayed Afterdepolarizations in the Canine Heart

N Jost, N Nagy, C Corici, Z Kohajda, A Horváth, K Acsai, P Biliczki, J Levijoki, P Pollesello, T Koskelainen, L Otsomaa, A Tóth, J Gy Papp, A Varró, L Virág

Br J Pharmacol. 2013 Oct;170(4):768-78.

PMID: 23647096

1

ORM-10103: A Significant Advance in Sodium-Calcium Exchanger Pharmacology?

C M Terracciano, J C Hancox

Br J Pharmacol. 2013 Oct;170(4):765-7.

PMID: 23848255

1

Paradoxical Effects of Sodium-Calcium Exchanger Inhibition on Torsade De Pointes and Early Afterdepolarization in a Heart Failure Rabbit Model

Po-Cheng Chang, Yu-Ying Lu, Hui-Ling Lee, Shien-Fong Lin, Yen Chu, Ming-Shien Wen, Chung-Chuan Chou

J Cardiovasc Pharmacol. 2018 Aug;72(2):97-105.

PMID: 29738372

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