CAS 160492-56-8 Osanetant - Analytical Products / Alfa Chemistry

CAT	AP160492568
CAS	160492-56-8
Structure
Molecular Weight	606.62

Description	≥98% (HPLC)
Solubility	DMSO: 15 mg/mL, clear
Assay	≥98% (HPLC)
Color	white to beige
Form	powder
Size	5MG, 25MG
Storage Conditions	−20°C

1

Gateways to Clinical Trials

M Bayes, X Rabasseda, J R Prous

Methods Find Exp Clin Pharmacol. 2002 Apr;24(3):159-84.

PMID: 12087878

1

Identification of a Critical Residue in the Transmembrane Domain 2 of Tachykinin Neurokinin 3 Receptor Affecting the Dissociation Kinetics and Antagonism Mode of Osanetant (SR 142801) and Piperidine-Based Structures

Pari Malherbe, Claudia Kratzeisen, Anne Marcuz, Marie-Thérèse Zenner, Matthias H Nettekoven, Hasane Ratni, Joseph G Wettstein, Caterina Bissantz

J Med Chem. 2009 Nov 26;52(22):7103-12.

PMID: 19817444

1

Me-talnetant and Osanetant Interact Within Overlapping but Not Identical Binding Pockets in the Human Tachykinin Neurokinin 3 Receptor Transmembrane Domains

Pari Malherbe, Caterina Bissantz, Anne Marcuz, Claudia Kratzeisen, Marie-Thérèse Zenner, Joseph G Wettstein, Hasane Ratni, Claus Riemer, Will Spooren

Mol Pharmacol. 2008 Jun;73(6):1736-50.

PMID: 18308898

1

Neurokinin-3 Receptor-Specific Antagonists Talnetant and Osanetant Show Distinct Mode of Action in Cellular Ca2+ Mobilization but Display Similar Binding Kinetics and Identical Mechanism of Binding in Ligand Cross-Competition

Gaochao Tian, Dee Wilkins, Clay W Scott

Mol Pharmacol. 2007 Mar;71(3):902-11.

PMID: 17172464

1

Osanetant Sanofi-Synthélabo

F Kamali

Curr Opin Investig Drugs. 2001 Jul;2(7):950-6.

PMID: 11757797

* Products or Services Interested: Osanetant (160492-56-8)
* Your question
* Name
* Email
Verification Code